diff --git a/_isa-md/README.md b/_isa-md/README.md
new file mode 100644
index 0000000000000000000000000000000000000000..5b042ab2590eb927eb07a2de284e30489e1ea5fa
--- /dev/null
+++ b/_isa-md/README.md
@@ -0,0 +1,14 @@
+# ISA Metadata as markdown tables
+
+:warning: This is just for convenience since .xlsx files are not shown in GitLab. Check the original `isa.*.xlsx` for latest metadata.
+
+
+## Convert xlsx to md
+
+For convenience (i.e. since `.xlsx` are not shown in GitLab), I wrote a [little helper tool](https://github.com/nfdi4plants/xlsx2markdownTable) that converts all xlsx into markdown tables.
+
+```bash
+xlsx2md -e "isa" -o _isa-md -d -di
+```
+
+:bulb: This collects all "isa" metadata it will find in a separate folder (in root).
\ No newline at end of file
diff --git a/_isa-md/assays/GCqTOF_targets/isa.assay/02_metabolites_extr.md b/_isa-md/assays/GCqTOF_targets/isa.assay/02_metabolites_extr.md
new file mode 100644
index 0000000000000000000000000000000000000000..08d18351b7774dac8fe6fd812835cca2e6f71186
--- /dev/null
+++ b/_isa-md/assays/GCqTOF_targets/isa.assay/02_metabolites_extr.md
@@ -0,0 +1,9 @@
+| Source Name   | Parameter [Bio entity]   |   Parameter [Biosource amount] | Unit (#2)   | Parameter [Biosource material state]   | Parameter [Extraction buffer]             |   Parameter [Extraction buffer volume] | Parameter [Internal standard]   |   Parameter [Sample volume] | Unit       | Parameter [MS sample post-extraction]   | Parameter [MS sample resuspension]   | Parameter [MS derivatization]                                                                                                                  | Parameter [label]   | Sample Name   |
+|:--------------|:-------------------------|-------------------------------:|:------------|:---------------------------------------|:------------------------------------------|---------------------------------------:|:--------------------------------|----------------------------:|:-----------|:----------------------------------------|:-------------------------------------|:-----------------------------------------------------------------------------------------------------------------------------------------------|:--------------------|:--------------|
+| CAM_01        | metabolites              |                            6.1 | milligram   | Dry material                           | water:methanol:chloroform 1:2.5:1 (v:v:v) |                                   1500 | ribitol                         |                          50 | microliter | dried in vacuum concentrator            | -                                    | (1) with 10 μl methoxyamine hydrochloride (Acros organics; freshly prepared at 20 mg/ml in pure pyridine (Sigma-Aldrich)) and shaking at 37 ◦C | -                   | DB23          |
+|               |                          |                                |             |                                        |                                           |                                        |                                 |                             |            |                                         |                                      | for 90 min, (2) adding 90 μl N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA; Macherey-Nagel) and shaking at 37 ◦C for 30 min.            |                     |               |
+| CAM_02        | metabolites              |                            5.2 | milligram   | Dry material                           | water:methanol:chloroform 1:2.5:1 (v:v:v) |                                   1500 | ribitol                         |                          50 | microliter | dried in vacuum concentrator            | -                                    | 10 μl methoxyamine hydrochloride and 90 μl N-Methyl-N-(trimethylsilyl)trifluoroacetamide MSTFA                                                 | -                   | DB24          |
+| CAM_03        | metabolites              |                            8.2 | milligram   | Dry material                           | water:methanol:chloroform 1:2.5:1 (v:v:v) |                                   1500 | ribitol                         |                          50 | microliter | dried in vacuum concentrator            | -                                    | MaHCl and MSTFA                                                                                                                                | -                   | DB26          |
+| reC3_01       | metabolites              |                            4.9 | milligram   | Dry material                           | water:methanol:chloroform 1:2.5:1 (v:v:v) |                                   1500 | ribitol                         |                          50 | microliter | dried in vacuum concentrator            | -                                    | methoxyamination + trimethylsylilation (TMS)                                                                                                   | -                   | DB39          |
+| reC3_02       | metabolites              |                            6   | milligram   | Dry material                           | water:methanol:chloroform 1:2.5:1 (v:v:v) |                                   1500 | ribitol                         |                          50 | microliter | dried in vacuum concentrator            | -                                    | methoxyamination + trimethylsylilation (TMS)                                                                                                   | -                   | DB40          |
+| reC3_03       | metabolites              |                            6.2 | milligram   | Dry material                           | water:methanol:chloroform 1:2.5:1 (v:v:v) |                                   1500 | ribitol                         |                          50 | microliter | dried in vacuum concentrator            | -                                    | methoxyamination + trimethylsylilation (TMS)                                                                                                   | -                   | DB41          |
\ No newline at end of file
diff --git a/_isa-md/assays/GCqTOF_targets/isa.assay/03_metabolites_chromatography.md b/_isa-md/assays/GCqTOF_targets/isa.assay/03_metabolites_chromatography.md
new file mode 100644
index 0000000000000000000000000000000000000000..d822c9c4a7b9b916fe87bdd2a68e5441b08e7b2b
--- /dev/null
+++ b/_isa-md/assays/GCqTOF_targets/isa.assay/03_metabolites_chromatography.md
@@ -0,0 +1,22 @@
+| Source Name   | Parameter [MS sample type]   | Parameter [Chromatography instrument model]   | Parameter [Chromatography autosampler model]   | Parameter [Chromatography column type]   | Parameter [Chromatography column model]   | Parameter [Chromatography guard column model]   | Parameter [mobile phase]   |   Parameter [Chromatography injection volume] | Unit       | Parameter [Chromatography injection mode]   | Parameter [Chromatography gradient]   |   Sample Name |
+|:--------------|:-----------------------------|:----------------------------------------------|:-----------------------------------------------|:-----------------------------------------|:------------------------------------------|:------------------------------------------------|:---------------------------|----------------------------------------------:|:-----------|:--------------------------------------------|:--------------------------------------|--------------:|
+| Std. Mix 5µM  |                              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-433                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150112_03 |
+| Std. Mix 5µM  |                              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-434                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150112_04 |
+| blank 1       |                              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-435                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150112_15 |
+| blank 1       |                              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-436                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150112_16 |
+| DB23          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-437                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150112_55 |
+| DB23          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-438                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150112_56 |
+| DB24          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-439                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150112_61 |
+| DB24          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-440                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150112_62 |
+| DB26          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-441                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150112_65 |
+| DB26          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-442                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150112_66 |
+| Std. Mix 5µM  |                              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-443                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150115_03 |
+| Std. Mix 5µM  |                              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-444                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150115_04 |
+| DB39          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-445                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150115_11 |
+| DB39          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-446                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150115_12 |
+| DB40          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-447                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150115_13 |
+| DB40          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-448                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150115_14 |
+| DB41          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-449                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150115_15 |
+| DB41          | material sample              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-450                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150115_16 |
+| blank 2       |                              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-451                        | -                                               | helium(0)                  |                                             1 | microliter | splitless                                   | gradient elution                      |     150115_25 |
+| blank 2       |                              | Agilent 7890B GC                              | GERSTEL MultiPurpose Sampler (MPS) Dual Head   | low polarity                             | Agilent 19091S-452                        | -                                               | helium(0)                  |                                             1 | microliter | split                                       | gradient elution                      |     150115_26 |
\ No newline at end of file
diff --git a/_isa-md/assays/GCqTOF_targets/isa.assay/04_metabolites_massspec.md b/_isa-md/assays/GCqTOF_targets/isa.assay/04_metabolites_massspec.md
new file mode 100644
index 0000000000000000000000000000000000000000..b8fbf5b50434a294cb6887f0bb564c7900d877ce
--- /dev/null
+++ b/_isa-md/assays/GCqTOF_targets/isa.assay/04_metabolites_massspec.md
@@ -0,0 +1,22 @@
+|   Source Name | Parameter [scan polarity]   |   Parameter [scan window lower limit] |   Parameter [scan window upper limit] |   Parameter [scan rate] | Unit   | Parameter [instrument model]        | Parameter [ionization type]   | Parameter [mass analyzer type]   | Parameter [detector type]   | Data File Name   |
+|--------------:|:----------------------------|--------------------------------------:|--------------------------------------:|------------------------:|:-------|:------------------------------------|:------------------------------|:---------------------------------|:----------------------------|:-----------------|
+|     150112_03 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_03.D      |
+|     150112_04 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_04.D      |
+|     150112_15 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_15.D      |
+|     150112_16 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_16.D      |
+|     150112_55 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_55.D      |
+|     150112_56 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_56.D      |
+|     150112_61 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_61.D      |
+|     150112_62 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_62.D      |
+|     150112_65 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_65.D      |
+|     150112_66 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150112_66.D      |
+|     150115_03 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_03.D      |
+|     150115_04 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_04.D      |
+|     150115_11 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_11.D      |
+|     150115_12 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_12.D      |
+|     150115_13 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_13.D      |
+|     150115_14 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_14.D      |
+|     150115_15 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_15.D      |
+|     150115_16 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_16.D      |
+|     150115_25 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_25.D      |
+|     150115_26 | positive                    |                                    60 |                                   800 |                      20 | hertz  | 7200 GC-QTOF (Agilent Technologies) | electron ionization           | quadrupole                       | electron multiplier         | 150115_26.D      |
\ No newline at end of file
diff --git a/_isa-md/assays/GCqTOF_targets/isa.assay/Assay.md b/_isa-md/assays/GCqTOF_targets/isa.assay/Assay.md
new file mode 100644
index 0000000000000000000000000000000000000000..11481b14f175d510670a32720be8a87efb324829
--- /dev/null
+++ b/_isa-md/assays/GCqTOF_targets/isa.assay/Assay.md
@@ -0,0 +1,6 @@
+| ASSAY METADATA   | Unnamed: 1                    | Unnamed: 2      | Unnamed: 3   | Unnamed: 4   | Unnamed: 5   |
+|:-----------------|:------------------------------|:----------------|:-------------|:-------------|:-------------|
+| Measurement Type | GCqTOF targeted               |                 |              |              |              |
+| File Name        | GCqTOF_targets/isa.assay.xlsx |                 |              |              |              |
+| Last Name        | Brilhaus                      | Mettler-Altmann | Klemp        | Graf         | Weber        |
+| First Name       | Dominik                       | Tabea           | Elisabeth    | Maria        | Katrin       |
\ No newline at end of file
diff --git a/_isa-md/assays/MassHunter_targets/isa.assay/05_metabolites_datatrans.md b/_isa-md/assays/MassHunter_targets/isa.assay/05_metabolites_datatrans.md
new file mode 100644
index 0000000000000000000000000000000000000000..e69de29bb2d1d6434b8b29ae775ad8c2e48c5391
diff --git a/_isa-md/assays/MassHunter_targets/isa.assay/06_metabolites_identification.md b/_isa-md/assays/MassHunter_targets/isa.assay/06_metabolites_identification.md
new file mode 100644
index 0000000000000000000000000000000000000000..e69de29bb2d1d6434b8b29ae775ad8c2e48c5391
diff --git a/_isa-md/assays/MassHunter_targets/isa.assay/Assay.md b/_isa-md/assays/MassHunter_targets/isa.assay/Assay.md
new file mode 100644
index 0000000000000000000000000000000000000000..9c512c21de6a780f4b164f7bc3437830f3ded7c3
--- /dev/null
+++ b/_isa-md/assays/MassHunter_targets/isa.assay/Assay.md
@@ -0,0 +1,3 @@
+| ASSAY METADATA   | Unnamed: 1                        |
+|:-----------------|:----------------------------------|
+| File Name        | MassHunter_targets/isa.assay.xlsx |
\ No newline at end of file
diff --git a/_isa-md/assays/MassHunter_targets/isa.datapackage/Derivations.md b/_isa-md/assays/MassHunter_targets/isa.datapackage/Derivations.md
new file mode 100644
index 0000000000000000000000000000000000000000..6eee651b791e699c9332987258af80e62ed6c693
--- /dev/null
+++ b/_isa-md/assays/MassHunter_targets/isa.datapackage/Derivations.md
@@ -0,0 +1,25 @@
+| Identifier      | TargetFile                                                                                                  | wasDerivedFrom                                                                                    | Unnamed: 3                                                                      |
+|:----------------|:------------------------------------------------------------------------------------------------------------|:--------------------------------------------------------------------------------------------------|:--------------------------------------------------------------------------------|
+| Data File       | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]05_metabolites_datatrans':Source Name                 | [./assays/GCqTOF_targets/isa.assay.xlsx]04_metabolites_massspec':Data File Name |
+| Sample Name     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/GCqTOF_targets/isa.assay.xlsx]03_metabolites_chromatography':Source Name                |                                                                                 |
+| Sample.Type     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/GCqTOF_targets/isa.assay.xlsx]03_metabolites_chromatography':Parameter [MS sample type] |                                                                                 |
+| Position        | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| Inj Vol         | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| Instrument      | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| Acq.Method.File | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| SpeedVacVol     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| Sample.Comment  | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| Sample.Approved | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| Compound        | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| ISTD            | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| Resp            | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| ISTD Resp       | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| Resp Ratio      | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| UserAnno.Peak   | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| MI.Peak         | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| MZ              | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| MZ.Ex.Left      | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| MZ.Ex.Right     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| MZ.Ex.Units     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| RT.Compound     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
+| RT.Peak         | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx |                                                                                                   |                                                                                 |
\ No newline at end of file
diff --git a/_isa-md/assays/MassHunter_targets/isa.datapackage/Dictionary.md b/_isa-md/assays/MassHunter_targets/isa.datapackage/Dictionary.md
new file mode 100644
index 0000000000000000000000000000000000000000..f0cc0f24c6b1051591dfd19330e86b000bce5726
--- /dev/null
+++ b/_isa-md/assays/MassHunter_targets/isa.datapackage/Dictionary.md
@@ -0,0 +1,26 @@
+| Identifier      | TargetFile                                                                                                  | wasGeneratedBy                                                             | Attribute [Term]                                   | Attribute          | Unit                             | Comment                                                                  |
+|:----------------|:------------------------------------------------------------------------------------------------------------|:---------------------------------------------------------------------------|:---------------------------------------------------|:-------------------|:---------------------------------|:-------------------------------------------------------------------------|
+| Data File       | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' |                                                    | ISA Data File Name |                                  |                                                                          |
+| Sample Name     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' |                                                    | ISA Sample Name    |                                  |                                                                          |
+| Sample.Type     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | MS sample type [NFDI4PSO:0000045]                  | MS sample type     |                                  |                                                                          |
+| Position        | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Vial position                                      |                    |                                  | Indicates the vial position (e.g. in the autosampler)                    |
+| Inj Vol         | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Chromatography injection volume [NFDI4PSO:0010014] |                    | microliter [UO_0000101]          |                                                                          |
+| Instrument      | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | instrument model [MS:1000031]                      |                    |                                  |                                                                          |
+| Acq.Method.File | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Acquisition Method File Name [User specific]       |                    |                                  | References the acquisition method used during GC-MS                      |
+| SpeedVacVol     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Sample volume [NFDI4PSO:0010013]                   |                    |                                  |                                                                          |
+| Sample.Comment  | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Quality check comment [User specific]              |                    |                                  | QC comment of sample                                                     |
+| Sample.Approved | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Quality check [User specific]                      |                    |                                  | QC of sample                                                             |
+| Compound        | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Compound [NCIT_C43366]                             |                    |                                  |                                                                          |
+| ISTD            | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Internal standard                                  |                    |                                  | see http://purl.obolibrary.org/obo/MSIO_0000005 (internal standard role) |
+| Resp            | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | peak intensity [MS_1000042]                        |                    | area under curve [STATO_0000209] | peak intensity of the Compound                                           |
+| ISTD Resp       | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | peak intensity [MS_1000042]                        |                    |                                  | peak intensity of the ISTD                                               |
+| Resp Ratio      | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | ratio [STATO_0000184]                              |                    |                                  | ratio of peak intensities of (compound : ISTD)                           |
+| UserAnno.Peak   | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Quality check comment [User specific]              |                    |                                  | QC comment of peak intensity                                             |
+| MI.Peak         | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | Quality check [User specific]                      |                    |                                  | QC of peak intensity                                                     |
+| MZ              | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | m/z [MS_1000040]                                   |                    |                                  | mass-to-charge ratio of extracted ion                                    |
+| MZ.Ex.Left      | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | isolation window lower offset [MS_1000828]         |                    |                                  |                                                                          |
+| MZ.Ex.Right     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | isolation window upper offset [MS_1000829]         |                    |                                  |                                                                          |
+| MZ.Ex.Units     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' |                                                    |                    |                                  |                                                                          |
+| RT.Compound     | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | retention time [MS_1000894]                        |                    |                                  | targeted retention time for compound                                     |
+| RT.Peak         | ./assays/MassHunter_targets/dataset/QuantReports/22-0005_exp001.batch_a.bin/190614_QuantReport_ISTD_DB.xlsx | [./assays/MassHunter_targets/isa.assay.xlsx]06_metabolites_identification' | retention time [MS_1000894]                        |                    |                                  | actual retention time, at which the peak for the compound was extracted  |
+|                 |                                                                                                             |                                                                            | Add to NFDI4PSO                                    |                    |                                  |                                                                          |
\ No newline at end of file
diff --git a/_isa-md/assays/Talinum_RNASeq_minimal/isa.assay/Assay.md b/_isa-md/assays/Talinum_RNASeq_minimal/isa.assay/Assay.md
new file mode 100644
index 0000000000000000000000000000000000000000..73eba7b7cfdbbaa77ed5b99ed24f131460f4e63a
--- /dev/null
+++ b/_isa-md/assays/Talinum_RNASeq_minimal/isa.assay/Assay.md
@@ -0,0 +1,19 @@
+| ASSAY METADATA                         | Unnamed: 1                                                        | Unnamed: 2                                      | Unnamed: 3                                      | Unnamed: 4                                         |
+|:---------------------------------------|:------------------------------------------------------------------|:------------------------------------------------|:------------------------------------------------|:---------------------------------------------------|
+| Measurement Type                       | mRNA Sequencing                                                   |                                                 |                                                 |                                                    |
+| Measurement Type Term Accession Number | http://purl.obolibrary.org/obo/NCIT_C129432                       |                                                 |                                                 |                                                    |
+| Measurement Type Term Source REF       | NCIT                                                              |                                                 |                                                 |                                                    |
+| Technology Type                        | Next Generation Sequencing                                        |                                                 |                                                 |                                                    |
+| Technology Type Term Accession Number  | http://purl.obolibrary.org/obo/NCIT_C101293                       |                                                 |                                                 |                                                    |
+| Technology Type Term Source REF        | NCIT                                                              |                                                 |                                                 |                                                    |
+| Technology Platform                    | Illumina HiSeq 2500                                               |                                                 |                                                 |                                                    |
+| File Name                              | Talinum_RNASeq_minimal/isa.assay.xlsx                             |                                                 |                                                 |                                                    |
+| Last Name                              | Brilhaus                                                          | Winter                                          | Kurz                                            | Wachtmeister                                       |
+| First Name                             | Dominik                                                           | Klaus                                           | Samantha                                        | Thorsten                                           |
+| Email                                  | dominik.brilhaus@hhu.de                                           |                                                 |                                                 |                                                    |
+| Phone                                  | 0211-8115523                                                      |                                                 |                                                 |                                                    |
+| Address                                | HHU Düsseldorf, 22.07.U1.43, Universitätsstr. 1, 40225 Düsseldorf | Balboa, Ancón, Republic of Panama               | Universitätsstr. 1, 40225 Düsseldorf            | Universitätsstr. 1, 40225 Düsseldorf               |
+| Affiliation                            | Institute of Plant Biochemistry, HHU Düsseldorf                   | Smithsonian Tropical Research Institute, Panama | Institute of Plant Biochemistry, HHU Düsseldorf | Biological Medical Research Centre, HHU Düsseldorf |
+| Roles                                  | research assistant                                                | co-investigator                                 | technician                                      | technician                                         |
+| Roles Term Accession Number            | http://purl.org/spar/scoro/research-assistant                     | http://purl.org/spar/scoro/co-investigator      | http://purl.org/spar/scoro/technician           | http://purl.org/spar/scoro/technician              |
+| Roles Term Source REF                  | scoro                                                             | scoro                                           | scoro                                           | scoro                                              |
\ No newline at end of file
diff --git a/_isa-md/assays/Talinum_RNASeq_minimal/isa.assay/illumina.md b/_isa-md/assays/Talinum_RNASeq_minimal/isa.assay/illumina.md
new file mode 100644
index 0000000000000000000000000000000000000000..4296ee396fa53821bb25e4c103a31b3fd2e85285
--- /dev/null
+++ b/_isa-md/assays/Talinum_RNASeq_minimal/isa.assay/illumina.md
@@ -0,0 +1,8 @@
+| Source Name   | Protocol Type   | Protocol REF   | Parameter [library strategy]   | Parameter [library selection]   | Parameter [library layout]   | Parameter [library preparation kit]   | Parameter [library preparation kit version]   | Parameter [adapter sequence]   | Parameter [next generation sequencing instrument model]   | Parameter [base-calling software]   | Parameter [base-calling software version]   | Parameter [Raw data file format]   | Raw Data File                              |
+|:--------------|:----------------|:---------------|:-------------------------------|:--------------------------------|:-----------------------------|:--------------------------------------|:----------------------------------------------|:-------------------------------|:----------------------------------------------------------|:------------------------------------|:--------------------------------------------|:-----------------------------------|:-------------------------------------------|
+| CAM_01_ext    | assay protocol  | illumina.md    | RNA-seq                        | cDNA method                     | single-end                   | Illumina TruSeq RNA Sample Prep Kit   | version 2                                     | CAGATC                         | Illumina HiSeq 2000                                       | Illumina Cassava                    | v1.8.2                                      | *.fastq.gz                         | DB_097_CAMMD_CAGATC_L001_R1_001.fastq.gz   |
+| CAM_02_ext    | assay protocol  | illumina.md    | RNA-seq                        | cDNA method                     | single-end                   | Illumina TruSeq RNA Sample Prep Kit   | version 2                                     | CTTGTA                         | Illumina HiSeq 2000                                       | Illumina Cassava                    | v1.8.2                                      | *.fastq.gz                         | DB_099_CAMMD_CTTGTA_L001_R1_001.fastq.gz   |
+| CAM_03_ext    | assay protocol  | illumina.md    | RNA-seq                        | cDNA method                     | single-end                   | Illumina TruSeq RNA Sample Prep Kit   | version 2                                     | AGTCAA                         | Illumina HiSeq 2000                                       | Illumina Cassava                    | v1.8.2                                      | *.fastq.gz                         | DB_103_CAMMD_AGTCAA_L001_R1_001.fastq.gz   |
+| reC3_01_ext   | assay protocol  | illumina.md    | RNA-seq                        | cDNA method                     | single-end                   | Illumina TruSeq RNA Sample Prep Kit   | version 2                                     | GTCCGC                         | Illumina HiSeq 2000                                       | Illumina Cassava                    | v1.8.2                                      | *.fastq.gz                         | DB_161_reC3MD_GTCCGC_L001_R1_001.fastq.gz  |
+| reC3_02_ext   | assay protocol  | illumina.md    | RNA-seq                        | cDNA method                     | single-end                   | Illumina TruSeq RNA Sample Prep Kit   | version 2                                     | GTGAAA                         | Illumina HiSeq 2000                                       | Illumina Cassava                    | v1.8.2                                      | *.fastq.gz                         | DB_163_reC3MD_GTGAAA_L001_R1_001.fastq.gz  |
+| reC3_03_ext   | assay protocol  | illumina.md    | RNA-seq                        | cDNA method                     | single-end                   | Illumina TruSeq RNA Sample Prep Kit   | version 2                                     | GTGAAA                         | Illumina HiSeq 2000                                       | Illumina Cassava                    | v1.8.2                                      | *.fastq.gz                         | DB_165_re-C3MD_GTGAAA_L002_R1_001.fastq.gz |
\ No newline at end of file
diff --git a/_isa-md/assays/Talinum_RNASeq_minimal/isa.assay/rna_extraction.md b/_isa-md/assays/Talinum_RNASeq_minimal/isa.assay/rna_extraction.md
new file mode 100644
index 0000000000000000000000000000000000000000..de23c8d130506ce61442276a58339156c44c7ad9
--- /dev/null
+++ b/_isa-md/assays/Talinum_RNASeq_minimal/isa.assay/rna_extraction.md
@@ -0,0 +1,8 @@
+| Source Name   | Protocol Type           | Protocol REF      |   Parameter [biosource amount] | Unit      | Parameter [extraction method]                                                  | Parameter [extraction buffer]   |   Parameter [extraction buffer volume] | Unit (#2)   | Parameter [RNA quality check]                            | Sample Name   |
+|:--------------|:------------------------|:------------------|-------------------------------:|:----------|:-------------------------------------------------------------------------------|:--------------------------------|---------------------------------------:|:------------|:---------------------------------------------------------|:--------------|
+| CAM_01        | RNA extraction protocol | rna_extraction.md |                             80 | milligram | Roboklon EURx GeneMATRIX Universal RNA Purification version 2.3 September 2011 | Roboklon commercial buffers     |                                    300 | microliter  | RIN 7.6 (Agilent Bioanalyzer 2100 expert_Plant RNA Nano) | CAM_01_ext    |
+| CAM_02        | RNA extraction protocol | rna_extraction.md |                             78 | milligram | Roboklon EURx GeneMATRIX Universal RNA Purification version 2.3 September 2011 | Roboklon commercial buffers     |                                    300 | microliter  | RIN 7.7 (Agilent Bioanalyzer 2100 expert_Plant RNA Nano) | CAM_02_ext    |
+| CAM_03        | RNA extraction protocol | rna_extraction.md |                             93 | milligram | Roboklon EURx GeneMATRIX Universal RNA Purification version 2.3 September 2011 | Roboklon commercial buffers     |                                    300 | microliter  | RIN 6.5 (Agilent Bioanalyzer 2100 expert_Plant RNA Nano) | CAM_03_ext    |
+| reC3_01       | RNA extraction protocol | rna_extraction.md |                             82 | milligram | Roboklon EURx GeneMATRIX Universal RNA Purification version 2.3 September 2011 | Roboklon commercial buffers     |                                    300 | microliter  | RIN 7.8 (Agilent Bioanalyzer 2100 expert_Plant RNA Nano) | reC3_01_ext   |
+| reC3_02       | RNA extraction protocol | rna_extraction.md |                             96 | milligram | Roboklon EURx GeneMATRIX Universal RNA Purification version 2.3 September 2011 | Roboklon commercial buffers     |                                    300 | microliter  | RIN 7.6 (Agilent Bioanalyzer 2100 expert_Plant RNA Nano) | reC3_02_ext   |
+| reC3_03       | RNA extraction protocol | rna_extraction.md |                             78 | milligram | Roboklon EURx GeneMATRIX Universal RNA Purification version 2.3 September 2011 | Roboklon commercial buffers     |                                    300 | microliter  | RIN 7.6 (Agilent Bioanalyzer 2100 expert_Plant RNA Nano) | reC3_03_ext   |
\ No newline at end of file
diff --git a/_isa-md/isa.investigation/isa_investigation.md b/_isa-md/isa.investigation/isa_investigation.md
new file mode 100644
index 0000000000000000000000000000000000000000..e8d4c84bab975b1dce1e39cfd555200dc9971401
--- /dev/null
+++ b/_isa-md/isa.investigation/isa_investigation.md
@@ -0,0 +1,73 @@
+| ONTOLOGY SOURCE REFERENCE                          | Unnamed: 1                                                                                                                                                                                                                  | Unnamed: 2                                                                                                                                                                                                                                                                                                                                                                                                                                                       | Unnamed: 3                                                                                                                                                                                                                  | Unnamed: 4                                                                                                                                                                                                                  | Unnamed: 5                                                                                                                                                                                                                                                                                                                                                                                                                                                       | Unnamed: 6                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      | Unnamed: 7                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      | Unnamed: 8                                                                                                                                                                                                                                                                                                                                      | Unnamed: 9                                                                                                                                                                          | Unnamed: 10                                                                                                                                                                         | Unnamed: 11   | Unnamed: 12   |
+|:---------------------------------------------------|:----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|:--------------|:--------------|
+| Term Source Name                                   | PECO                                                                                                                                                                                                                        | UO                                                                                                                                                                                                                                                                                                                                                                                                                                                               | NFDI4PSO                                                                                                                                                                                                                    |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Term Source File                                   | http://purl.obolibrary.org/obo/peco.owl                                                                                                                                                                                     | http://purl.obolibrary.org/obo/uo.owl                                                                                                                                                                                                                                                                                                                                                                                                                            | https://github.com/nfdi4plants/nfdi4plants_ontology/blob/main/nfdi4plants_ontology.obo                                                                                                                                      |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Term Source Version                                | releases/2020-08-21                                                                                                                                                                                                         | releases/2020-03-10                                                                                                                                                                                                                                                                                                                                                                                                                                              |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Term Source Description                            | Plant Experimental Conditions Ontology                                                                                                                                                                                      | Unit ontology                                                                                                                                                                                                                                                                                                                                                                                                                                                    | NFDI for Plant Science Ontology                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Identifier                           | samplearc_rnaseq                                                                                                                                                                                                            |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Title                                | Facultative CAM in Talinum triangulare                                                                                                                                                                                      |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Submission Date                      | July 07, 2015                                                                                                                                                                                                               |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Public Release Date                  | Nov 05, 2015                                                                                                                                                                                                                |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Publication PubMed ID                | 26530316                                                                                                                                                                                                                    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Publication DOI                      | 10.1104/pp.15.01076                                                                                                                                                                                                         |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Publication Author List              | Brilhaus, Dominik; Bräutigam, Andrea; Mettler-Altmann, Tabea; Winter, Klaus; Weber, Andreas P M                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Publication Title                    | Reversible Burst of Transcriptional Changes during Induction of Crassulacean Acid Metabolism in Talinum triangulare.                                                                                                        |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Publication Status                   | Published                                                                                                                                                                                                                   |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person Last Name                     | Brilhaus                                                                                                                                                                                                                    | Bräutigam                                                                                                                                                                                                                                                                                                                                                                                                                                                        | Mettler-Altmann                                                                                                                                                                                                             | Winter                                                                                                                                                                                                                      | Weber                                                                                                                                                                                                                                                                                                                                                                                                                                                            |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person First Name                    | Dominik                                                                                                                                                                                                                     | Andrea                                                                                                                                                                                                                                                                                                                                                                                                                                                           | Tabea                                                                                                                                                                                                                       | Klaus                                                                                                                                                                                                                       | Andreas                                                                                                                                                                                                                                                                                                                                                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person Mid Initials                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             | P M                                                                                                                                                                                                                                                                                                                                                                                                                                                              |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person Email                         | dominik.brilhaus@hhu.de                                                                                                                                                                                                     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person Phone                         | 0211-8115523                                                                                                                                                                                                                |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person Address                       | HHU Düsseldorf, 22.07.U1.43, Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                           | Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                                                                                                                                                                                                                                                             | Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                        | Balboa, Ancón, Republic of Panama                                                                                                                                                                                           | Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                                                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person Affiliation                   | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                             | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                                                                                                                                                                                                                                                                  | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                             | Smithsonian Tropical Research Institute, Panama                                                                                                                                                                             | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person Roles                         | research assistant                                                                                                                                                                                                          | research assistant                                                                                                                                                                                                                                                                                                                                                                                                                                               | research assistant                                                                                                                                                                                                          | co-investigator                                                                                                                                                                                                             | principal investigator                                                                                                                                                                                                                                                                                                                                                                                                                                           |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person Roles Term Accession Number   | http://purl.org/spar/scoro/research-assistant                                                                                                                                                                               | http://purl.org/spar/scoro/research-assistant                                                                                                                                                                                                                                                                                                                                                                                                                    | http://purl.org/spar/scoro/research-assistant                                                                                                                                                                               | http://purl.org/spar/scoro/co-investigator                                                                                                                                                                                  | http://purl.org/spar/scoro/principal-investigator                                                                                                                                                                                                                                                                                                                                                                                                                |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Investigation Person Roles Term Source REF         | scoro                                                                                                                                                                                                                       | scoro                                                                                                                                                                                                                                                                                                                                                                                                                                                            | scoro                                                                                                                                                                                                                       | scoro                                                                                                                                                                                                                       | scoro                                                                                                                                                                                                                                                                                                                                                                                                                                                            |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Comment[<Investigation Person ORCID>]              | http://orcid.org/0000-0001-9021-3197                                                                                                                                                                                        | http://orcid.org/0000-0002-5309-0527                                                                                                                                                                                                                                                                                                                                                                                                                             | http://orcid.org/0000-0002-9161-4889                                                                                                                                                                                        |                                                                                                                                                                                                                             | http://orcid.org/0000-0003-0970-4672                                                                                                                                                                                                                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Identifier                                   | TalinumFacultativeCAM                                                                                                                                                                                                       |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study File Name                                    | TalinumFacultativeCAM/isa.study.xlsx                                                                                                                                                                                        |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Factor Name                                  | watering exposure                                                                                                                                                                                                           | Timepoint                                                                                                                                                                                                                                                                                                                                                                                                                                                        | timepoint-ZT                                                                                                                                                                                                                | Photosynthesis mode                                                                                                                                                                                                         |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Factor Type                                  | watering exposure                                                                                                                                                                                                           | Timepoint                                                                                                                                                                                                                                                                                                                                                                                                                                                        | timepoint-ZT                                                                                                                                                                                                                | Photosynthesis mode                                                                                                                                                                                                         |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Factor Type Term Accession Number            | http://purl.obolibrary.org/obo/PECO_0007383                                                                                                                                                                                 | http://purl.obolibrary.org/obo/NCIT_C68568                                                                                                                                                                                                                                                                                                                                                                                                                       |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Factor Type Term Source REF                  | PECO                                                                                                                                                                                                                        | NCIT                                                                                                                                                                                                                                                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Assay Measurement Type                       | mRNA Sequencing                                                                                                                                                                                                             | GCqTOF targeted                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Assay Measurement Type Term Accession Number | http://purl.obolibrary.org/obo/NCIT_C129432                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Assay Measurement Type Term Source REF       | NCIT                                                                                                                                                                                                                        |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Assay Technology Type                        | Next Generation Sequencing                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Assay Technology Type Term Accession Number  | http://purl.obolibrary.org/obo/NCIT_C101293                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Assay Technology Type Term Source REF        | NCIT                                                                                                                                                                                                                        |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Assay Technology Platform                    | Illumina HiSeq 2500                                                                                                                                                                                                         |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Assay File Name                              | Talinum_RNASeq_minimal/isa.assay.xlsx                                                                                                                                                                                       | GCqTOF_targets/isa.assay.xlsx                                                                                                                                                                                                                                                                                                                                                                                                                                    | MassHunter_targets/isa.assay.xlsx                                                                                                                                                                                           |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Protocol Name                                | rna_extraction                                                                                                                                                                                                              | illumina                                                                                                                                                                                                                                                                                                                                                                                                                                                         | plant_material.md                                                                                                                                                                                                           | rna_extraction.md                                                                                                                                                                                                           | illumina.md                                                                                                                                                                                                                                                                                                                                                                                                                                                      | 02_metabolites_extr                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             | 03_metabolites_chromatography                                                                                                                                                                                                                                                                                                                                                                                                                                                                   | 04_metabolites_massspec                                                                                                                                                                                                                                                                                                                         | 05_metabolites_datatrans                                                                                                                                                            | 06_metabolites_identification                                                                                                                                                       |               |               |
+| Study Protocol Type                                |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | plant growth protocol                                                                                                                                                                                                       | RNA extraction protocol                                                                                                                                                                                                     | assay protocol                                                                                                                                                                                                                                                                                                                                                                                                                                                   |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Protocol Type Term Accession Number          |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | http://purl.obolibrary.org/obo/DPBO_1000164                                                                                                                                                                                 | http://purl.obolibrary.org/obo/DPBO_1000173                                                                                                                                                                                 | http://purl.obolibrary.org/obo/DPBO_1000177                                                                                                                                                                                                                                                                                                                                                                                                                      |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Protocol Type Term Source REF                |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | DPBO                                                                                                                                                                                                                        | DPBO                                                                                                                                                                                                                        | DPBO                                                                                                                                                                                                                                                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Protocol Parameters Name                     | biosource amount;extraction method;extraction buffer;extraction buffer volume;RNA quality check                                                                                                                             | library strategy;library selection;library layout;library preparation kit;library preparation kit version;adapter sequence;next generation sequencing instrument model;base-calling software;base-calling software version;Raw data file format                                                                                                                                                                                                                  | growth day length;light intensity exposure;humidity day;temperature day;temperature night                                                                                                                                   | biosource amount;extraction method;extraction buffer;extraction buffer volume;RNA quality check                                                                                                                             | library strategy;library selection;library layout;library preparation kit;library preparation kit version;adapter sequence;next generation sequencing instrument model;base-calling software;base-calling software version;Raw data file format                                                                                                                                                                                                                  | Bio entity;Biosource amount;Biosource material state;Extraction buffer;Extraction buffer volume;Internal standard;Sample volume;MS sample post-extraction;MS sample resuspension;MS derivatization;label                                                                                                                                                                                                                                                                                                                                        | MS sample type;Chromatography instrument model;Chromatography autosampler model;Chromatography column type;Chromatography column model;Chromatography guard column model;mobile phase;Chromatography injection volume;Chromatography injection mode;Chromatography gradient                                                                                                                                                                                                                     | scan polarity;scan window lower limit;scan window upper limit;scan rate;instrument model;ionization type;mass analyzer type;detector type                                                                                                                                                                                                       | area normalization;data transformation;Metabolite Assignment File;Processed data file format                                                                                        | area normalization;data transformation;Metabolite Assignment File;Processed data file format                                                                                        |               |               |
+| Study Protocol Parameters Term Accession Number    | http://purl.obolibrary.org/obo/DPBO_0000013;http://purl.obolibrary.org/obo/DPBO_0000054;http://purl.obolibrary.org/obo/DPBO_0000050;http://purl.obolibrary.org/obo/DPBO_0000051;http://purl.obolibrary.org/obo/DPBO_0000062 | http://purl.obolibrary.org/obo/DPBO_0000035;http://purl.obolibrary.org/obo/DPBO_0000036;http://purl.obolibrary.org/obo/DPBO_0000015;http://purl.obolibrary.org/obo/GENEPIO_0000085;http://purl.obolibrary.org/obo/GENEPIO_0000149;http://purl.obolibrary.org/obo/GENEPIO_0000083;http://purl.obolibrary.org/obo/DPBO_0000040;http://purl.obolibrary.org/obo/DPBO_0000017;http://purl.obolibrary.org/obo/DPBO_0000018;http://purl.obolibrary.org/obo/DPBO_0000021 | http://purl.obolibrary.org/obo/DPBO_0000041;http://purl.obolibrary.org/obo/PECO_0007224;http://purl.obolibrary.org/obo/DPBO_0000005;http://purl.obolibrary.org/obo/DPBO_0000007;http://purl.obolibrary.org/obo/DPBO_0000008 | http://purl.obolibrary.org/obo/DPBO_0000013;http://purl.obolibrary.org/obo/DPBO_0000054;http://purl.obolibrary.org/obo/DPBO_0000050;http://purl.obolibrary.org/obo/DPBO_0000051;http://purl.obolibrary.org/obo/DPBO_0000062 | http://purl.obolibrary.org/obo/DPBO_0000035;http://purl.obolibrary.org/obo/DPBO_0000036;http://purl.obolibrary.org/obo/DPBO_0000015;http://purl.obolibrary.org/obo/GENEPIO_0000085;http://purl.obolibrary.org/obo/GENEPIO_0000149;http://purl.obolibrary.org/obo/GENEPIO_0000083;http://purl.obolibrary.org/obo/DPBO_0000040;http://purl.obolibrary.org/obo/DPBO_0000017;http://purl.obolibrary.org/obo/DPBO_0000018;http://purl.obolibrary.org/obo/DPBO_0000021 | http://purl.obolibrary.org/obo/NFDI4PSO_0000012;http://purl.obolibrary.org/obo/NFDI4PSO_0000013;http://purl.obolibrary.org/obo/NFDI4PSO_0010009;http://purl.obolibrary.org/obo/NFDI4PSO_0000050;http://purl.obolibrary.org/obo/NFDI4PSO_0000051;http://purl.obolibrary.org/obo/NFDI4PSO_0010012;http://purl.obolibrary.org/obo/NFDI4PSO_0010013;http://purl.obolibrary.org/obo/NFDI4PSO_0000043;http://purl.obolibrary.org/obo/NFDI4PSO_0000044;http://purl.obolibrary.org/obo/NFDI4PSO_0000052;http://purl.obolibrary.org/obo/NFDI4PSO_0000079 | http://purl.obolibrary.org/obo/NFDI4PSO_0000045;http://purl.obolibrary.org/obo/NFDI4PSO_0000046;http://purl.obolibrary.org/obo/NFDI4PSO_0000047;http://purl.obolibrary.org/obo/NFDI4PSO_0000053;http://purl.obolibrary.org/obo/NFDI4PSO_0000048;http://purl.obolibrary.org/obo/NFDI4PSO_0000049;http://purl.obolibrary.org/obo/NFDI4PSO_0000080;http://purl.obolibrary.org/obo/NFDI4PSO_0010014;http://purl.obolibrary.org/obo/NFDI4PSO_0010015;http://purl.obolibrary.org/obo/NFDI4PSO_0000081 | http://purl.obolibrary.org/obo/MS_1000465;http://purl.obolibrary.org/obo/MS_1000501;http://purl.obolibrary.org/obo/MS_1000500;http://purl.obolibrary.org/obo/MS_1000015;http://purl.obolibrary.org/obo/MS_1000031;http://purl.obolibrary.org/obo/MS_1000008;http://purl.obolibrary.org/obo/MS_1000443;http://purl.obolibrary.org/obo/MS_1000026 | http://purl.obolibrary.org/obo/MS_1001999;http://purl.obolibrary.org/obo/MS_1000452;http://purl.obolibrary.org/obo/NFDI4PSO_0000077;http://purl.obolibrary.org/obo/NFDI4PSO_0000027 | http://purl.obolibrary.org/obo/MS_1001999;http://purl.obolibrary.org/obo/MS_1000452;http://purl.obolibrary.org/obo/NFDI4PSO_0000077;http://purl.obolibrary.org/obo/NFDI4PSO_0000027 |               |               |
+| Study Protocol Parameters Term Source REF          | DPBO;DPBO;DPBO;DPBO;DPBO                                                                                                                                                                                                    | DPBO;DPBO;DPBO;GENEPIO;GENEPIO;GENEPIO;DPBO;DPBO;DPBO;DPBO                                                                                                                                                                                                                                                                                                                                                                                                       | DPBO;PECO;DPBO;DPBO;DPBO                                                                                                                                                                                                    | DPBO;DPBO;DPBO;DPBO;DPBO                                                                                                                                                                                                    | DPBO;DPBO;DPBO;GENEPIO;GENEPIO;GENEPIO;DPBO;DPBO;DPBO;DPBO                                                                                                                                                                                                                                                                                                                                                                                                       | NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO                                                                                                                                                                                                                                                                                                                                                                                                                                              | NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO;NFDI4PSO                                                                                                                                                                                                                                                                                                                                                                                                       | MS;MS;MS;MS;MS;MS;MS;MS                                                                                                                                                                                                                                                                                                                         | MS;MS;NFDI4PSO;NFDI4PSO                                                                                                                                                             | MS;MS;NFDI4PSO;NFDI4PSO                                                                                                                                                             |               |               |
+| Comment[<RowRange>]                                |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | 0:5                                                                                                                                                                                                                         | 0:5                                                                                                                                                                                                                         | 0:5                                                                                                                                                                                                                                                                                                                                                                                                                                                              | 0:5                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                             | 0:19                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            | 0:19                                                                                                                                                                                                                                                                                                                                            | 0:0                                                                                                                                                                                 | 0:0                                                                                                                                                                                 |               |               |
+| Study Person Last Name                             | Brilhaus                                                                                                                                                                                                                    | Winter                                                                                                                                                                                                                                                                                                                                                                                                                                                           | Kurz                                                                                                                                                                                                                        | Wachtmeister                                                                                                                                                                                                                |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | Brilhaus                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                        | Winter                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          | Brilhaus                                                                                                                                                                                                                                                                                                                                        | Mettler-Altmann                                                                                                                                                                     | Klemp                                                                                                                                                                               | Graf          | Weber         |
+| Study Person First Name                            | Dominik                                                                                                                                                                                                                     | Klaus                                                                                                                                                                                                                                                                                                                                                                                                                                                            | Samantha                                                                                                                                                                                                                    | Thorsten                                                                                                                                                                                                                    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | Dominik                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         | Klaus                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           | Dominik                                                                                                                                                                                                                                                                                                                                         | Tabea                                                                                                                                                                               | Elisabeth                                                                                                                                                                           | Maria         | Katrin        |
+| Study Person Email                                 | dominik.brilhaus@hhu.de                                                                                                                                                                                                     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | dominik.brilhaus@hhu.de                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Phone                                 | 0211-8115523                                                                                                                                                                                                                |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | 0211-8115523                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                    |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Address                               | HHU Düsseldorf, 22.07.U1.43, Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                           | Balboa, Ancón, Republic of Panama                                                                                                                                                                                                                                                                                                                                                                                                                                | Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                        | Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                        |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | HHU Düsseldorf, 22.07.U1.43, Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                                                                                                                                                                                                                                                                                                               | Balboa, Ancón, Republic of Panama                                                                                                                                                                                                                                                                                                                                                                                                                                                               |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Affiliation                           | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                             | Smithsonian Tropical Research Institute, Panama                                                                                                                                                                                                                                                                                                                                                                                                                  | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                             | Biological Medical Research Centre, HHU Düsseldorf                                                                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 | Smithsonian Tropical Research Institute, Panama                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Roles                                 | research assistant                                                                                                                                                                                                          | co-investigator                                                                                                                                                                                                                                                                                                                                                                                                                                                  | technician                                                                                                                                                                                                                  | technician                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | research assistant                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                              | co-investigator                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Roles Term Accession Number           | http://purl.org/spar/scoro/research-assistant                                                                                                                                                                               | http://purl.org/spar/scoro/co-investigator                                                                                                                                                                                                                                                                                                                                                                                                                       | http://purl.org/spar/scoro/technician                                                                                                                                                                                       | http://purl.org/spar/scoro/technician                                                                                                                                                                                       |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | http://purl.org/spar/scoro/research-assistant                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   | http://purl.org/spar/scoro/co-investigator                                                                                                                                                                                                                                                                                                                                                                                                                                                      |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Roles Term Source REF                 | scoro                                                                                                                                                                                                                       | scoro                                                                                                                                                                                                                                                                                                                                                                                                                                                            | scoro                                                                                                                                                                                                                       | scoro                                                                                                                                                                                                                       |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | scoro                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           | scoro                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Comment[<Study Person ORCID>]                      |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | http://orcid.org/0000-0001-9021-3197                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Identifier                                   | TalinumGenomeDraft                                                                                                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study File Name                                    | TalinumGenomeDraft/isa.study.xlsx                                                                                                                                                                                           |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Protocol Name                                | TalinumGenomeDraft                                                                                                                                                                                                          |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Comment[<RowRange>]                                | 0:0                                                                                                                                                                                                                         |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Last Name                             | Maleckova                                                                                                                                                                                                                   | Brilhaus                                                                                                                                                                                                                                                                                                                                                                                                                                                         | Denton                                                                                                                                                                                                                      | Weber                                                                                                                                                                                                                       |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person First Name                            | Eva                                                                                                                                                                                                                         | Dominik                                                                                                                                                                                                                                                                                                                                                                                                                                                          | Alisandra                                                                                                                                                                                                                   | Andreas                                                                                                                                                                                                                     |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Mid Initials                          |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  | K                                                                                                                                                                                                                           | P M                                                                                                                                                                                                                         |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Email                                 |                                                                                                                                                                                                                             | dominik.brilhaus@hhu.de                                                                                                                                                                                                                                                                                                                                                                                                                                          |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Phone                                 |                                                                                                                                                                                                                             | 0211-8115523                                                                                                                                                                                                                                                                                                                                                                                                                                                     |                                                                                                                                                                                                                             |                                                                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Address                               | Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                        | HHU Düsseldorf, 22.07.U1.43, Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                                                                                                                                                                                                                                | Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                        | Universitätsstr. 1, 40225 Düsseldorf                                                                                                                                                                                        |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Affiliation                           | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                             | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                                                                                                                                                                                                                                                                  | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                             | Institute of Plant Biochemistry, HHU Düsseldorf                                                                                                                                                                             |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Roles                                 | research assistant                                                                                                                                                                                                          | research assistant                                                                                                                                                                                                                                                                                                                                                                                                                                               | research assistant                                                                                                                                                                                                          | principal investigator                                                                                                                                                                                                      |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Roles Term Accession Number           | http://purl.org/spar/scoro/research-assistant                                                                                                                                                                               | http://purl.org/spar/scoro/research-assistant                                                                                                                                                                                                                                                                                                                                                                                                                    | http://purl.org/spar/scoro/research-assistant                                                                                                                                                                               | http://purl.org/spar/scoro/principal-investigator                                                                                                                                                                           |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Study Person Roles Term Source REF                 | scoro                                                                                                                                                                                                                       | scoro                                                                                                                                                                                                                                                                                                                                                                                                                                                            | scoro                                                                                                                                                                                                                       | scoro                                                                                                                                                                                                                       |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
+| Comment[<Study Person ORCID>]                      | https://orcid.org/0000-0001-9062-3516                                                                                                                                                                                       | http://orcid.org/0000-0001-9021-3197                                                                                                                                                                                                                                                                                                                                                                                                                             |                                                                                                                                                                                                                             | http://orcid.org/0000-0003-0970-4672                                                                                                                                                                                        |                                                                                                                                                                                                                                                                                                                                                                                                                                                                  |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                                                                                                                                                                                 |                                                                                                                                                                                     |                                                                                                                                                                                     |               |               |
\ No newline at end of file
diff --git a/_isa-md/runs/kallisto_collect/out/isa.dataset/Dictionary.md b/_isa-md/runs/kallisto_collect/out/isa.dataset/Dictionary.md
new file mode 100644
index 0000000000000000000000000000000000000000..d2c2a934a14242e35ce5c4232f2f21bc8d33ae1b
--- /dev/null
+++ b/_isa-md/runs/kallisto_collect/out/isa.dataset/Dictionary.md
@@ -0,0 +1,14 @@
+| Data Pointer    | Data File Name                      | wasGeneratedBy              | Attribute                    | ObjectType   | Label                        | Comment                                    |
+|:----------------|:------------------------------------|:----------------------------|:-----------------------------|:-------------|:-----------------------------|:-------------------------------------------|
+| target_id       | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | gene identifier              | String       | Gene ID                      | Gene identifier, reference to fasta        |
+| pval            | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | p-value                      | Decimal      | P-Value                      | Pvalue, has a term                         |
+| qval            | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | q-value                      | Decimal      | Q-Value                      | qVal, has a term                           |
+| test_stat       | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | test statistic               | Decimal      | Test Statistic               | test statisitc, has a term                 |
+| rss             | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | residual                     | Decimal      | Residual sum of squares      | residual sum of squares, has a term        |
+| degrees_free    | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | number of degrees of freedom | Integer      | Number Of Degrees Of Freedom | degrees of freedom, has a term             |
+| mean_obs        | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | mean                         | Decimal      | Mean                         | mean of observations, needs references     |
+| var_obs         | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | variance                     | Decimal      | Variance                     | variance of observations, needs references |
+| tech_var        | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | variance                     | Decimal      | Technical variance           | technical variance? Has a term             |
+| sigma_sq        | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | variance                     | Decimal      | Variance                     | variance of observations, needs references |
+| smooth_sigma_sq | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | smoothed variance            | Decimal      | Smoothed Variance            | smoothed variance                          |
+| final_sigma_sq  | runs/kallisto_sleuth/sleuth_dge.csv | workflows/kallisto_sleuth.R | corrected variance           | Decimal      | Corrected Variance           | adjusted variance                          |
\ No newline at end of file
diff --git a/_isa-md/runs/kallisto_sleuth/isa.dataset/Dictionary.md b/_isa-md/runs/kallisto_sleuth/isa.dataset/Dictionary.md
new file mode 100644
index 0000000000000000000000000000000000000000..d9e464d12e6238a8bd6c1649e28f3ec20df8b022
--- /dev/null
+++ b/_isa-md/runs/kallisto_sleuth/isa.dataset/Dictionary.md
@@ -0,0 +1,14 @@
+| Data Pointer    | Data File Name                          | wasGeneratedBy                              | Attribute                    | ObjectType   | Label                        | Comment                                    |
+|:----------------|:----------------------------------------|:--------------------------------------------|:-----------------------------|:-------------|:-----------------------------|:-------------------------------------------|
+| target_id       | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | gene identifier              | String       | Gene ID                      | Gene identifier, reference to fasta        |
+| pval            | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | p-value                      | Decimal      | P-Value                      | Pvalue, has a term                         |
+| qval            | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | q-value                      | Decimal      | Q-Value                      | qVal, has a term                           |
+| test_stat       | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | test statistic               | Decimal      | Test Statistic               | test statisitc, has a term                 |
+| rss             | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | residual                     | Decimal      | Residual sum of squares      | residual sum of squares, has a term        |
+| degrees_free    | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | number of degrees of freedom | Integer      | Number Of Degrees Of Freedom | degrees of freedom, has a term             |
+| mean_obs        | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | mean                         | Decimal      | Mean                         | mean of observations, needs references     |
+| var_obs         | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | variance                     | Decimal      | Variance                     | variance of observations, needs references |
+| tech_var        | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | variance                     | Decimal      | Technical variance           | technical variance? Has a term             |
+| sigma_sq        | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | variance                     | Decimal      | Variance                     | variance of observations, needs references |
+| smooth_sigma_sq | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | smoothed variance            | Decimal      | Smoothed Variance            | smoothed variance                          |
+| final_sigma_sq  | runs/kallisto_sleuth/out/sleuth_dge.csv | workflows/kallisto_sleuth/kallisto_sleuth.R | corrected variance           | Decimal      | Corrected Variance           | adjusted variance                          |
\ No newline at end of file
diff --git a/_isa-md/studies/TalinumFacultativeCAM/isa.study/Study.md b/_isa-md/studies/TalinumFacultativeCAM/isa.study/Study.md
new file mode 100644
index 0000000000000000000000000000000000000000..226516dccf8e08e71c92e0eb09cb42176461d8dd
--- /dev/null
+++ b/_isa-md/studies/TalinumFacultativeCAM/isa.study/Study.md
@@ -0,0 +1,14 @@
+| STUDY METADATA                           | Unnamed: 1                                                        | Unnamed: 2                                      |
+|:-----------------------------------------|:------------------------------------------------------------------|:------------------------------------------------|
+| Study Identifier                         | TalinumFacultativeCAM                                             |                                                 |
+| Study File Name                          | TalinumFacultativeCAM/isa.study.xlsx                              |                                                 |
+| Study Person Last Name                   | Brilhaus                                                          | Winter                                          |
+| Study Person First Name                  | Dominik                                                           | Klaus                                           |
+| Study Person Email                       | dominik.brilhaus@hhu.de                                           |                                                 |
+| Study Person Phone                       | 0211-8115523                                                      |                                                 |
+| Study Person Address                     | HHU Düsseldorf, 22.07.U1.43, Universitätsstr. 1, 40225 Düsseldorf | Balboa, Ancón, Republic of Panama               |
+| Study Person Affiliation                 | Institute of Plant Biochemistry, HHU Düsseldorf                   | Smithsonian Tropical Research Institute, Panama |
+| Study Person Roles                       | research assistant                                                | co-investigator                                 |
+| Study Person Roles Term Accession Number | http://purl.org/spar/scoro/research-assistant                     | http://purl.org/spar/scoro/co-investigator      |
+| Study Person Roles Term Source REF       | scoro                                                             | scoro                                           |
+| Comment[<Study Person ORCID>]            | http://orcid.org/0000-0001-9021-3197                              |                                                 |
\ No newline at end of file
diff --git a/_isa-md/studies/TalinumFacultativeCAM/isa.study/plant_material.md b/_isa-md/studies/TalinumFacultativeCAM/isa.study/plant_material.md
new file mode 100644
index 0000000000000000000000000000000000000000..97e5515c16b3010c2faeb3dd18f5b49662a85166
--- /dev/null
+++ b/_isa-md/studies/TalinumFacultativeCAM/isa.study/plant_material.md
@@ -0,0 +1,8 @@
+| Source Name   | Protocol REF      | Protocol Type         | Characteristic [organism]   | Characteristic [organism part]   | Characteristic [plant age]   | Parameter [growth day length]   |   Parameter [light intensity exposure] | Unit                                      |   Parameter [humidity day] | Unit    |   Parameter [temperature day] | Unit           |   Parameter [temperature night] | Unit           | Factor [watering exposure]         | Factor [Timepoint]   |   Factor [timepoint-ZT] | Factor [Photosynthesis mode]   | Sample Name   |
+|:--------------|:------------------|:----------------------|:----------------------------|:---------------------------------|:-----------------------------|:--------------------------------|---------------------------------------:|:------------------------------------------|---------------------------:|:--------|------------------------------:|:---------------|--------------------------------:|:---------------|:-----------------------------------|:---------------------|------------------------:|:-------------------------------|:--------------|
+| DB_097        | plant_material.md | plant growth protocol | Talinum fruticosum          | leaf                             | 28 days after germination    | 12 hr light / 12 hr dark        |                                    425 | microeinstein per square meter per second |                         37 | percent |                            30 | degree celsius |                              22 | degree celsius | 12 days drought                    | MD                   |                       6 | CAM                            | CAM_01        |
+| DB_099        | plant_material.md | plant growth protocol | Talinum fruticosum          | leaf                             | 28 days after germination    | 12 hr light / 12 hr dark        |                                    425 | microeinstein per square meter per second |                         37 | percent |                            30 | degree celsius |                              22 | degree celsius | 12 days drought                    | MD                   |                       6 | CAM                            | CAM_02        |
+| DB_103        | plant_material.md | plant growth protocol | Talinum fruticosum          | leaf                             | 28 days after germination    | 12 hr light / 12 hr dark        |                                    425 | microeinstein per square meter per second |                         37 | percent |                            30 | degree celsius |                              22 | degree celsius | 12 days drought                    | MD                   |                       6 | CAM                            | CAM_03        |
+| DB_161        | plant_material.md | plant growth protocol | Talinum fruticosum          | leaf                             | 28 days after germination    | 12 hr light / 12 hr dark        |                                    425 | microeinstein per square meter per second |                         37 | percent |                            30 | degree celsius |                              22 | degree celsius | 12 days drought + 2 days rewatered | MD                   |                       6 | reC3                           | reC3_01       |
+| DB_163        | plant_material.md | plant growth protocol | Talinum fruticosum          | leaf                             | 28 days after germination    | 12 hr light / 12 hr dark        |                                    425 | microeinstein per square meter per second |                         37 | percent |                            30 | degree celsius |                              22 | degree celsius | 12 days drought + 2 days rewatered | MD                   |                       6 | reC3                           | reC3_02       |
+| DB_165        | plant_material.md | plant growth protocol | Talinum fruticosum          | leaf                             | 28 days after germination    | 12 hr light / 12 hr dark        |                                    425 | microeinstein per square meter per second |                         37 | percent |                            30 | degree celsius |                              22 | degree celsius | 12 days drought + 2 days rewatered | MD                   |                       6 | reC3                           | reC3_03       |
\ No newline at end of file
diff --git a/_isa-md/studies/TalinumGenomeDraft/isa.study/Study.md b/_isa-md/studies/TalinumGenomeDraft/isa.study/Study.md
new file mode 100644
index 0000000000000000000000000000000000000000..bfdc69daadbb5badc6b55711685fa5639abbef04
--- /dev/null
+++ b/_isa-md/studies/TalinumGenomeDraft/isa.study/Study.md
@@ -0,0 +1,15 @@
+| STUDY METADATA                           | Unnamed: 1                                      | Unnamed: 2                                                        | Unnamed: 3                                      | Unnamed: 4                                        |
+|:-----------------------------------------|:------------------------------------------------|:------------------------------------------------------------------|:------------------------------------------------|:--------------------------------------------------|
+| Study Identifier                         | TalinumGenomeDraft                              |                                                                   |                                                 |                                                   |
+| Study File Name                          | TalinumGenomeDraft/isa.study.xlsx               |                                                                   |                                                 |                                                   |
+| Study Person Last Name                   | Maleckova                                       | Brilhaus                                                          | Denton                                          | Weber                                             |
+| Study Person First Name                  | Eva                                             | Dominik                                                           | Alisandra                                       | Andreas                                           |
+| Study Person Mid Initials                |                                                 |                                                                   | K                                               | P M                                               |
+| Study Person Email                       |                                                 | dominik.brilhaus@hhu.de                                           |                                                 |                                                   |
+| Study Person Phone                       |                                                 | 0211-8115523                                                      |                                                 |                                                   |
+| Study Person Address                     | Universitätsstr. 1, 40225 Düsseldorf            | HHU Düsseldorf, 22.07.U1.43, Universitätsstr. 1, 40225 Düsseldorf | Universitätsstr. 1, 40225 Düsseldorf            | Universitätsstr. 1, 40225 Düsseldorf              |
+| Study Person Affiliation                 | Institute of Plant Biochemistry, HHU Düsseldorf | Institute of Plant Biochemistry, HHU Düsseldorf                   | Institute of Plant Biochemistry, HHU Düsseldorf | Institute of Plant Biochemistry, HHU Düsseldorf   |
+| Study Person Roles                       | research assistant                              | research assistant                                                | research assistant                              | principal investigator                            |
+| Study Person Roles Term Accession Number | http://purl.org/spar/scoro/research-assistant   | http://purl.org/spar/scoro/research-assistant                     | http://purl.org/spar/scoro/research-assistant   | http://purl.org/spar/scoro/principal-investigator |
+| Study Person Roles Term Source REF       | scoro                                           | scoro                                                             | scoro                                           | scoro                                             |
+| Comment[<Study Person ORCID>]            | https://orcid.org/0000-0001-9062-3516           | http://orcid.org/0000-0001-9021-3197                              |                                                 | http://orcid.org/0000-0003-0970-4672              |
\ No newline at end of file
diff --git a/_isa-md/studies/TalinumGenomeDraft/isa.study/TalinumGenomeDraft.md b/_isa-md/studies/TalinumGenomeDraft/isa.study/TalinumGenomeDraft.md
new file mode 100644
index 0000000000000000000000000000000000000000..fd5a8245d4ae7c02f4443f62a58388aae61cab48
--- /dev/null
+++ b/_isa-md/studies/TalinumGenomeDraft/isa.study/TalinumGenomeDraft.md
@@ -0,0 +1,3 @@
+| Source Name             | Derived Data File    |
+|:------------------------|:---------------------|
+| VariousTalinumData[WIP] | Talinum.gm.CDS.nt.fa |
\ No newline at end of file