diff --git a/workflows/deseq2/Dockerfile b/workflows/deseq2/Dockerfile
index 277379d367a919713bac7a7446616b250769acab..fb3edf185ab1df36a475ff87f2507ecb1e537a68 100644
--- a/workflows/deseq2/Dockerfile
+++ b/workflows/deseq2/Dockerfile
@@ -1,7 +1,5 @@
-FROM quay.io/biocontainers/bioconductor-deseq2:1.42.0--r43hf17093f_2
-
-# Since our base image is an R docker base we will use BiocManager install
+FROM rstudio/r-base:4.3-jammy
 
 RUN apt-get update && \ 
-    R -e "install.packages(c('BiocManager'), repos='https://cloud.r-project.org/');BiocManager::install('tximport')" && \
+    R -e "install.packages(c('BiocManager'), repos='https://cloud.r-project.org/'); BiocManager::install('DESeq2'); BiocManager::install('tximport'); BiocManager::install('rhdf5'); \\" && \
     apt-get clean -y
\ No newline at end of file