From f33bcf5d682b5f7aafa518b00f3d4499239999f1 Mon Sep 17 00:00:00 2001 From: Dominik Brilhaus <brilhaus@nfdi4plants.org> Date: Tue, 3 Dec 2024 07:30:56 +0000 Subject: [PATCH] Update README.md --- README.md | 3 +++ 1 file changed, 3 insertions(+) diff --git a/README.md b/README.md index cd3113e..a6c8ead 100644 --- a/README.md +++ b/README.md @@ -1,5 +1,8 @@ # Identification of nuclear pore proteins at plasmodesmata +[](https://doi.org/10.60534/46qra-6bw98) + + ## Abstract Here we used bioinformatics, proteomics and fluorescence imaging to identify proteins with similarities to phase separating FG-NUPs at PD. We identified 20 NUPs in PD fractions, and validated dual localization to NPC and PD for 7 NUPs. Structured illumination microscopy detected the transmembrane anchor NUP CPR5 at both orifices of PD. cpr5 mutants showed reduced intercellular transport of SHR from stele to endodermis. The identification of FG-NUPs at PD is consistent with the recruitment of NUPs in the green lineage to form a PD pore gating complex consistent with liquid phase separation domains as diffusion barriers at PD. -- GitLab