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["ONTOLOGY SOURCE REFERENCE"]
["Term Source Name"]
["Term Source File"]
["Term Source Version"]
["Term Source Description"]
["INVESTIGATION"]
["Investigation Identifier","VonDahlen-2023"]
["Investigation Title","Global expression patterns of {R}-genes in tomato and potato"]
["Investigation Description","The study explores how resistance genes (R-genes) in tomato and potato plants respond to pathogen infection by analyzing the expression of 940 R-genes across 315 transcriptome libraries. Results show that most R-genes are expressed at low levels, with a subset showing moderate to high expression across various conditions, regardless of infection. This subset includes NRCs (NLR required for cell death). About 10% of R-genes were differentially expressed during infection, with both up- and down-regulation patterns. Tissue-specific expression emerged as a key factor influencing R-gene activity. The findings challenge the belief that R-gene expression is primarily induced by pathogen attack, suggesting instead that a core set of R-genes is constitutively active, providing plants with a constant state of readiness for defense."]
["Investigation Submission Date"]
["Investigation Public Release Date","Sat Oct 28 2023 00:00:00 GMT+0200 (Central European Summer Time)"]
["INVESTIGATION PUBLICATIONS"]
["Investigation Publication PubMed ID"]
["Investigation Publication DOI","10.3389/fpls.2023.1216795"]
["Investigation Publication Author List","Von Dahlen, Janina K. and Schulz, Kerstin and Nicolai, Jessica and Rose, Laura E."]
["Investigation Publication Title","Global expression patterns of {R}-genes in tomato and potato"]
["Investigation Publication Status"]
["Investigation Publication Status Term Accession Number"]
["Investigation Publication Status Term Source REF"]
["INVESTIGATION CONTACTS"]
["Investigation Person Last Name","Von Dahlen","Schulz","Nicolai","Rose"]
["Investigation Person First Name","Janina K.","Kerstin","Jessica","Laura E."]
["Investigation Person Mid Initials"]
["Investigation Person Email",{"$nulls":3},"laura.rose@hhu.de"]
["Investigation Person Phone"]
["Investigation Person Fax"]
["Investigation Person Address"]
["Investigation Person Affiliation","Institute of Population Genetics, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany; iGRAD-Plant Graduate School, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany","Institute of Population Genetics, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany; Ceplas, Cluster of Excellence in Plant Sciences, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany","Institute of Population Genetics, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany","Institute of Population Genetics, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany; Ceplas, Cluster of Excellence in Plant Sciences, Heinrich-Heine University Duesseldorf, Duesseldorf, Germany"]
["Investigation Person Roles"]
["Investigation Person Roles Term Accession Number"]
["Investigation Person Roles Term Source REF"]