Explore ARCs
-
-
The trace element iron is essential for life, but elevated levels can rapidly cause cellular damage through oxidative stress. Bacteria, like Corynebacterium glutamicum, tightly regulate iron and heme homeostasis via the global regulators DtxR and HrrA. This study provides the first analysis of the genome-wide binding patterns of these two regulators demonstrating significant differences in binding dependent on the tested iron regimes. Overall, we identified 25 new DtxR targets and 210 previously unknown HrrA targets, including genes with crucial roles in central metabolism and DNA repair. Notably, DtxR was shown to link iron metabolism to methionine synthesis, which might be important to protect the cell from oxidative stress. Our findings highlight the interconnected nature of DtxR and HrrA networks and underscore the value of condition-specific analysis to deepen the understanding of how bacteria adapt to environmental changes.
Updated -
Identification of nuclear pore proteins at plasmodesmata
Updated -
Updated
-
Identification of nuclear pore proteins at plasmodesmata
Updated -
Cofunctioning of bacterial exometabolites drives root microbiota establishment
Updated -
early maturity 7 controls photoperiodic flowering in barley by modifying the diurnal expression pattern of the major photoperiod response gene Ppd-H1.
Updated -
This is the ARC resulting from the Start Here guide in the DataPLANT Knowledge Base.
Updated -
A prototypic ARC that implements all specification standards accordingly
Updated -
RoPod, a customizable toolkit for non-invasive root imaging, reveals cell type-specific dynamics of plant autophagy
Updated -
-
early maturity 7 controls photoperiodic flowering in barley by modifying the diurnal expression pattern of the major photoperiod response gene Ppd-H1.
Updated -
Updated
-
RNA seq from Solanum lycopersicoides plants, performed for the manuscript entitled "A Solanum lycopersicoides reference genome facilitates insights into tomato specialized metabolism and immunity."
Updated -
-
"QUINOA DIVERSITY- Quinoa Phenotypic and Genotypic Diversity for Yield and Composition"
Updated