From 64544af12a196dc15de59d1c334ab484caee6a2e Mon Sep 17 00:00:00 2001
From: Senthil-Kumar Devan <devan@hhu.de>
Date: Mon, 16 Dec 2024 18:15:46 +0100
Subject: [PATCH] xx

---
 .../isa.assay.xlsx                            | Bin 6912 -> 6913 bytes
 .../isa.assay.xlsx                            | Bin 6922 -> 6923 bytes
 .../isa.assay.xlsx                            | Bin 6930 -> 6931 bytes
 .../isa.assay.xlsx                            | Bin 6942 -> 6943 bytes
 .../isa.assay.xlsx                            | Bin 6933 -> 6934 bytes
 .../isa.assay.xlsx                            | Bin 6916 -> 6917 bytes
 .../isa.assay.xlsx                            | Bin 6958 -> 6959 bytes
 .../isa.assay.xlsx                            | Bin 6923 -> 6923 bytes
 .../isa.assay.xlsx                            | Bin 6945 -> 6945 bytes
 .../isa.assay.xlsx                            | Bin 6953 -> 6954 bytes
 isa.investigation.xlsx                        | Bin 7917 -> 7918 bytes
 .../isa.study.xlsx                            | Bin 7537 -> 7538 bytes
 .../isa.study.xlsx                            | Bin 7552 -> 7553 bytes
 .../isa.study.xlsx                            | Bin 7535 -> 7536 bytes
 .../isa.study.xlsx                            | Bin 7543 -> 7544 bytes
 .../isa.study.xlsx                            | Bin 7537 -> 7538 bytes
 .../isa.study.xlsx                            | Bin 7529 -> 7530 bytes
 17 files changed, 0 insertions(+), 0 deletions(-)

diff --git a/assays/S1_A1_Protein structure prediction/isa.assay.xlsx b/assays/S1_A1_Protein structure prediction/isa.assay.xlsx
index 3ac008e75682857d36ead8926322a8dbc98e2fb6..8a278e849d8163e93db04b21f5c57a6217171de0 100644
GIT binary patch
delta 662
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delta 662
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diff --git a/assays/S1_A2_Protein Purification for structural studies/isa.assay.xlsx b/assays/S1_A2_Protein Purification for structural studies/isa.assay.xlsx
index 563f9946de9bf75f8161ab0f4c41708ddffdff88..c092ca5442e5c246e32fb5ff738aa4baaba1b90c 100644
GIT binary patch
delta 654
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delta 653
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diff --git a/assays/S1_A3_Size exclusion chromatography of H-Rrm4-MLLE3/isa.assay.xlsx b/assays/S1_A3_Size exclusion chromatography of H-Rrm4-MLLE3/isa.assay.xlsx
index ea29e6ddbd66280a114c8bf8945af4d641898afe..cfc206ca46602c148cb2fe8a0038af44de0b3e2a 100644
GIT binary patch
delta 631
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delta 630
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diff --git a/assays/S1_A4_Western blot analysis of GST pull-down experiments with MLLE3 versions/isa.assay.xlsx b/assays/S1_A4_Western blot analysis of GST pull-down experiments with MLLE3 versions/isa.assay.xlsx
index 562ee0df0b6b8eb57b5f97dddb3ae3c43878e4ce..a61ad8f96af03b21f0672109191a645c2f5fa3b6 100644
GIT binary patch
delta 631
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delta 630
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diff --git a/assays/S1_A5_Isothermal Titration Calorimetry_ITC_using Rrm4 MLLE3/isa.assay.xlsx b/assays/S1_A5_Isothermal Titration Calorimetry_ITC_using Rrm4 MLLE3/isa.assay.xlsx
index f6cfb2eeee5bd73871628ed77a2f6661f17f0035..2efde3b0a709463f8d8c88dbf73aa6628e776a5e 100644
GIT binary patch
delta 647
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delta 646
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diff --git a/assays/S1_A6_X-ray structure of Rrm4-MLLE3/isa.assay.xlsx b/assays/S1_A6_X-ray structure of Rrm4-MLLE3/isa.assay.xlsx
index efb084d91631f87705b07f918ff5e67182a42e1e..1b541d104c1b50bc72d8a050a964fac2c6da1b2c 100644
GIT binary patch
delta 647
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delta 646
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diff --git a/assays/S1_A7_Multiple sequence alignment of Rrm4-MLLE3 orthologs of representative fungi from Basidiomycota/isa.assay.xlsx b/assays/S1_A7_Multiple sequence alignment of Rrm4-MLLE3 orthologs of representative fungi from Basidiomycota/isa.assay.xlsx
index 6333384dc8de8e9372f9195c44e311f10531e32a..9b42e31fd31edae9f22af9ab69c8f83937bddfe4 100644
GIT binary patch
delta 631
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delta 630
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diff --git a/assays/S2_A1_Structural analysis of MLLE3 of Rrm4/isa.assay.xlsx b/assays/S2_A1_Structural analysis of MLLE3 of Rrm4/isa.assay.xlsx
index 828449fa334923ace132ca53ff2bf4a30900a9bf..9a8b661e1953276d3be91558fc3a5ebc26ac27dd 100644
GIT binary patch
delta 647
zcmeA+>o(&F@MdP=Vqjq4VEEFxk*9-^=}YJ2X^cuhYV$5e0WkLrlRQZDEt4upRD@X`
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U3ar;t$_5ely;5Ksj!C%!05j<viU0rr

delta 647
zcmeA+>o(&F@MdP=Vqjq4VAxi$k*9-^X<NbMX^cuhYV$5e0WkLrlRQZDEt4upRD@X`
zENaT41>z>M>|g@X((Eh2!pAtks@`(!W&;VY;-3$ap6o3I7A_Lnz{s(!U_zwsQ46=p
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diff --git a/assays/S2_A2_Western blot analysis of GST pull-down experiments with MLLE3 variants/isa.assay.xlsx b/assays/S2_A2_Western blot analysis of GST pull-down experiments with MLLE3 variants/isa.assay.xlsx
index 8f26df46579c7f9961401368faeacce883748868..b070428abd1726a6c9c31c8b909b3d06e46d0d3b 100644
GIT binary patch
delta 616
zcmZ2zw$O|xz?+$ci-CcGgW*f(MxG8vrZ1h7r!gu4sm;3>1;E@hO!6Snw@j)aQ4wZ&
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nB^^K%NZCY5u(CChVAI}8T0$gDK~%hy4I*+EOMz{;BjpMJViglZ

delta 616
zcmZ2zw$O|xz?+$ci-CcGgW*lVMxG8vrZ)wXr!gu4sm;3>1;E@hO!6Snw@j)aQ4wZ&
zu&61E7Koe3vV#dkOSA6>3*X@Yt77Kd%?1)az&{@(JvmVbEZiZqfsx})!Gy>q?7wR!
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nNe2)GQZ`W%tZa=W*tEBjmJkV35EU<FgNWS4QeYeINVx(4on#If

diff --git a/assays/S2_A3_Western blot analysis of GST pull-down experiments with GST-MLLE3 and PAM2L variants/isa.assay.xlsx b/assays/S2_A3_Western blot analysis of GST pull-down experiments with GST-MLLE3 and PAM2L variants/isa.assay.xlsx
index 202f9374e1bc61e3bcea4f652fef77d18185aa4e..7a68c6c2bde027018ac4e75220a4bdaf3bbf3d24 100644
GIT binary patch
delta 664
zcmZ2!w#tkrz?+$ci-CcGgW*f(MxG8vrZ1h7r!gu4sm;3>1;E@hO!6Snw@j)aQ4wZ&
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delta 663
zcmZ2ww$h9zz?+$ci-CcGgF&@$BTok-lWO7QX^cuhYV$5e0WkLrlRQZDEt4upRD@X`
zENaT41>z>M>|g@X((EU|!cRHCs(3hevw?(9^3MlJPtFno3r`f<z{sguI3ZH*a&B+j
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diff --git a/isa.investigation.xlsx b/isa.investigation.xlsx
index c3df95ce3a8c45b39fef319ad28b085cdce8b67f..08e0de048779fa4ed994e5540ce9549d2355d5f2 100644
GIT binary patch
delta 657
zcmaEB`_7gpz?+$ci-CcGgW+@MMxG8vrq7*|r!gu4sm;3>1;E@hO!6Sng*>7{@kOaQ
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delta 655
zcmaE7`_`5xz?+$ci-CcGgCQYxBTok-Q$p(GX^cuhYV$5e0WkLrlRQXtA&;m~d{Jsn
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R*fRN;oD!R$G%x`&008ff1$h7f

diff --git a/studies/S1_MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain/isa.study.xlsx b/studies/S1_MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain/isa.study.xlsx
index 8987d6551beeb370a86dc6da18b1af24683a36db..cfbd505167521ef7228516b2ca19cbc9fc31457b 100644
GIT binary patch
delta 631
zcmexp^~s7Sz?+$ci-CcGgW*f(MxG8vrZ1h7r!gu4sm;3>1;E@hO!6Snw@j)aQ4wZ&
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B7W@DJ

delta 630
zcmexl_0ftaz?+$ci-CcGgCQYxBTok-Q$p(GX^cuhYV$5e0WkLrlRQZDEt4upRD@X`
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diff --git a/studies/S2_MLLE3 of Rrm4 Recognizes PAM2-Like Sequences with a Defined Binding Pocket/isa.study.xlsx b/studies/S2_MLLE3 of Rrm4 Recognizes PAM2-Like Sequences with a Defined Binding Pocket/isa.study.xlsx
index 1b1291067e1e4c44e296de5289394ef1c70ff4b9..00edfdf8d29f55d5eb6741298844863649d635c7 100644
GIT binary patch
delta 631
zcmZp$ZnWkJ@MdP=Vqjq4VEEFxk*9-^=}YJ2X^cuhYV$5e0WkLrlRQZDEt4upRD@X`
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B72yB?

delta 630
zcmZp)Zm{MF@MdP=Vqjq4U`R;a$kV~dl#n`k8lw`B+PsTV0L(qZBo7jO%cKet6=9YK
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zbhEld7dXB)OWK3t=ZmBfh|-WU2T_Sq`XH)9MrQIlDM=9Xq?8+o5|p+AQNGeHAZoI-
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diff --git a/studies/S3_Identifying an Essential FxY Core in PAM2-Like Peptides of Upa1/isa.study.xlsx b/studies/S3_Identifying an Essential FxY Core in PAM2-Like Peptides of Upa1/isa.study.xlsx
index b7b38561035d5d640c4b9a236a734bfc72b02497..e8d6801747d74485c4ef1a317dae7ca589c60d49 100644
GIT binary patch
delta 631
zcmaEF^}&iKz?+$ci-CcGgW*f(MxG8vrZ1h7r!gu4sm;3>1;E@hO!6Snw@j)aQ4wZ&
zu&61E7Koe3@`o8j$8(%u0;$sE2CE9--pvLQ<`tR`7G5U;7QQO7k&*LD=Y&X|G!4i2
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zluz0sZDaU;^6}+gC#5{ju;G1NC~^MU$5^5JYL{PZepeY#Z>F=${omUPqZiMl|D1j!
zjvT3*MJ2kx5w=j$9uz^3B#l6nn3Oq)@|V&FQ4Lb2AZojm8;JTZWd)+FrCmT&qqGBv
zYLJqdd|z4;#QY@<HpyDX5+*T81}w2w#s(>NKgpPZ<h5jF7`Z09%PO%=kpw0*1^`g{
B7tH_w

delta 629
zcmexh_1=mnz?+$ci-CcGgCQYxBTok-Q$p(GX^cuhYV$5e0WkLrlRQZDEt4upRD@X`
zENaT41>z>M{9y*s@f;_ZK&mvk!Kwndce8<nd4=YKh1ZFIg|CWiWaLapoe=47y!wCK
z<bE;D`pFFeqOA&BMVBjuYK5-87gNot*O`0M+xg$VbIlA|%kPzyr5*oWu+1hc^#k)Y
z&$VJI^ITLIj&7Z>Dq_O+vs!!98=aT2Xm4#|%{(wMwQhRh<f7b%N3)p4RCgSZ)|_6n
zS;5+6a?q<Ed|J=c;uhNMyt*yv#X{W`i8bfB7I=!B&19`V!Q$)|efUC8U&;oNnk^>m
z(PeB+!5RyhTKkSoo-uDL$F?GKZmVZbk)Am`cc#oc5m;MNByz3PcIEQ9SH8<%?*IBZ
z+dNAnbhj3t%6S(5ovdxQp5<q)FIj6;H8Hz#N`%wBrR^8o-+lPXEA#scM~%*bLT%n(
z)?c559-5!b@4I$wLHxYEPH&e=I4#V*9Gw2d@ubYUzdN@J9dRyx_f>x?@9wwh41z!A
zF8Rymf9Cg>kC~g5Duq-x8~7cn*w;C^#LRc`kIip?uKJe~!Q21m_Qw>1Gv#0PKgT1-
z>1HvBE^vG;lC%fK&tpj=5G5{U4x$32^g&dklqrbXA>{_7CP`a?I5yHQAgW2)0Yo)Q
z$xMDAEeT@&mIfPSBV!4Zm@EU9SSMqH6t|yc%s}$mvNDXElRadW*d|K?lNkd5`LF#;

diff --git a/studies/S4_MLLE3 of Rrm4 Is Necessary and Sufficient for Endosomal Attachment/isa.study.xlsx b/studies/S4_MLLE3 of Rrm4 Is Necessary and Sufficient for Endosomal Attachment/isa.study.xlsx
index fd058f9c64d9ffb3ee33ab642ca501e37170689b..e62f0924521d6e7d399eaa94f02807a10af0e945 100644
GIT binary patch
delta 710
zcmexv^}~uMz?+$ci-CcGgW*f(MxG8vrZ1h7r!gu4sm;3>1;E@hO!6R6LvB%__@dOD
zVtr&in?;!A!KzGIv_P5?S^hAC=y;9`Ob}hFAZ`TrZZ;4tDl{J~yiEiwd{<;6qtKVm
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zQ2~zFm6G<Lh<qh!1ft}m%t2JRls<^6laZOcL`o9G+%M$@qS&RaK$Nqz3yA8Jb^uWz
zWzVI-%9v!pra8-4LL^K<)K(cAPIxMq{7c469>ha;5ztXkAT-%uR*7wnB!~+DSEeLJ

delta 669
zcmexi_1%gmz?+$ci-CcGgCQYxBTok-Q$p(GX^cuhYV$5e0WkLrlRQY&kXuwJz9==P
zSRYx>W)Wt2uqsm)Es&-}mOsoOI-cVK6GWFPh#SGZn+-&Z3e5)#ZxaCv-xb-&$eEBj
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zHk+{256ss**NUmkb5UV9x^=>;hzZ-zYVA>PbY8}yy|sxo^T5Q^y6J_Ji*g?x&0-c)
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zDH}v;wwSO-m$5YkYb<1H?K?Jk#=NZ@+ltJ&t)4kWdgk!lnKJK0U~Nf}$hA`2mCNT|
z`7VFC|Lf;$^DK?f-CBGq=UM!BvbNoNmY=o0WUW!v#O%r`5l;7(wqJ06_u(tA%<nH8
zH97|hwRwM8e|-{qXnr!k@7lEm@$>dNy<IBdv@rK_aQYL+lQQf6?%XbP#JTw0SN*BH
zyWgfW2>zJ6<S(25ncrVNW^Puh6jI%6;CHBEU+3f!GvCEOHoyJ3>R(O-Z~vd$A5#p@
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zNV|ZjE@=l41yc4x8mx?225g#(j3q?E6hv*4u|bO5-!f+Mps41uF>#G$WMC*^VqoA0
SraS}?oE#vl#5P+JBmw}5-2pKG

diff --git a/studies/S5_Deciphering the Binding Code for MLLE of Pab1 and MLLE3 of Rrm4/isa.study.xlsx b/studies/S5_Deciphering the Binding Code for MLLE of Pab1 and MLLE3 of Rrm4/isa.study.xlsx
index c962215afd7f09a44e7e3df15c9572ae9c5aa12f..53087a7250dbc34ffde4c0bb474372e76b8a9355 100644
GIT binary patch
delta 631
zcmexp^~s7Sz?+$ci-CcGgW*f(MxG8vrZ1h7r!gu4sm;3>1;E@hO!6Snw@j)aQ4wZ&
zu&61E7Koe3@`o8j$8(%w0;$sG2CE9<-pvLQ<`<d|7TzEN7QQaBk&*LD=Y&X|G!4i2
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z963@qi%WEYBW$sxJt%^nNE(4C2`O_B6)2?-qAFx$CeM?S1Tl9?xq&D~X)6$AEA0ZJ
znx!2;6iC@aX|S?C(qPkUWh@~QrXXs)j15xkevvT)3F^qoF!D_HlvQGzCJ9Vv3;+x*
B7W@DJ

delta 630
zcmexl_0ftaz?+$ci-CcGgCQYxBTok-Q$p(GX^cuhYV$5e0WkLrlRQZDEt4upRD@X`
zENaT41>z>M{9y*s@f@d^K&rI4!K#9|ce8<n`Gw|#g*S+Rg|CZjWaLapoe=47y!wCK
z<cVUM^^+R{L|YZMiY`|Q)e2pGFQ%GPuQT_ixAVV!=b9O`mftHYOFRC%V4F=?>Idd)
zo@>Qa=DDaa9Nju$Rm6ntXSMdIH##q4(cap`nt5PiYTfk0$wj#jk7hB8sqQ!+tvS7D
zvx2qD<e*nS__Us>#Vxeid39UTi-o!?5^K(LE$|dMo5@;#g2mY_`tXIGzLX6jHCs&B
zqs!Quf;AR0we}sGJY(Kgj%`Ke+*Z$=B0Y0>?o63?BCxikNaR|n?aJkIuY8xk-2e4+
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z2M`5P_DCA6?5{M~G&>nfh=eJK+8|?t6uDnz%s_&=vNDX^lf7h>*rrMX(-{K*3kUsr

diff --git a/studies/S6_Identification of Unrecognized Rrm4 Interaction Partners/isa.study.xlsx b/studies/S6_Identification of Unrecognized Rrm4 Interaction Partners/isa.study.xlsx
index f46bf098cc58f48a260938c099a856382e587c44..0c6fb79e5590214610684b43ed40dcd7f574e02b 100644
GIT binary patch
delta 654
zcmaE9^~#DTz?+$ci-CcGgW*f(MxG8vrZ1h7r!gu4sm;3>1;E@hO!6Snw@j)aQ4wZ&
zu&61E7Koe3@`o8j$8#KF0;y8w2CMSo-pvLQW*3?d7G5C&7CtYsk&*LD=Y&X|G!4i2
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zUbw$fm7TM`&o*S~wnGV(Weu;q4O`Z33-z8mk=?R*$EWA_JOuc!?!3M~<ks75a~WM8
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zjvT3*`6ar*5jI=W9uz@$B#l6nfRs6i@|4mCQ3WzGlcz~Zf|whn+(6V%DJu|VD(wQI
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O%VbAcCAL0EkO%<0Dj2!|

delta 653
zcmaE5_0ozbz?+$ci-CcGgCQYxBTok-Q$p(GX^cuhYV$5e0WkLrlRQZDEt4upRD@X`
zENaT41>z>M{9y*s@f?SkK&q6v!K%Etce8<n*@fnVg;$7xh0lv@WaLapoe=47y!wCK
z<W4co`pFFeqOA&BMVBjuYK5-87gNot*O`0M+xg$VbIlA|%kPzyr5*oWu+1hc^#k)Y
z&$VJI^ITLIj&7Z>Dq_O+vs!!98=aT2Xm4#|%{(wMwQhRh<f7b%N3)p4RCgSZ)|_6n
zS;5+6a?q<Ed|J=c;uhNMyt*yv#X{W`i8bfB7I=!B&19`V!Q$)|efUC8U&;oNnk^>m
z(PeB+!5RyhTKkSoo-uDL$F?GKZmVZbk)Am`cc#oc5m;MNByz3PcIEQ9SH8<%?*IBZ
z+dNAnbhj3t%6S(5ovdxQp5<q)FIj6;H8Hz#N`%wBrR^8o-+lPXEA#scM~%*bLT%n(
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zF8Rymf9Cg>kC~g5Duq-x8~7cn*w;C^#LRc`kIip?uKJe~!Q21m_Qw>1Gv#0PKgT1-
z>1F|mE^vI!k+cWJ&s|9)5G5#O4x+rI^g&dijLhWeQj#F%CMh=%^-IbMM43sufT$X2
z2M`5Pc1s$p?5i}`G&31Xh=eJKS|MYD6uEC@%;Z5)&1GZa8q3JQP{PE(zz<Am2*5nq
MNmhxiR}v%w0CCCxHvj+t

-- 
GitLab