Explore ARCs

An example of a trial containing traits that have been scored multiple times over a period of time.

RNA seq from Solanum lycopersicoides plants, performed for the manuscript entitled "A Solanum lycopersicoides reference genome facilitates insights into tomato specialized metabolism and immunity."

Microtubule-dependent endosomal transport is crucial for polar growth, ensuring the precise distribution of cellular cargos such as proteins and mRNAs. However, the molecular mechanism linking mRNAs to the endosomal surface remains poorly understood. Here, we present a structural analysis of the key RNA-binding protein Rrm4 from Ustilago maydis. Our findings reveal a different type of MademoiseLLE domain (MLLE) featuring a seven-helical bundle that provides a distinct binding interface. A comparative analysis with the canonical MademoiseLLE domain of the poly(A)-binding protein Pab1 disclosed unique characteristics of both domains. Deciphering the MLLE binding code enabled prediction and verification of previously unknown Rrm4 interactors containing short linear motifs. Importantly, we demonstrated that the human MLLE domains, such as those of PABPC1 and UBR5, employed a similar principle to distinguish among interaction partners. Thus, our study provides detailed mechanistic insights into how structural variations in the widely distributed MLLE domain facilitate mRNA attachment during endosomal transport.

Algae cultures were grown mixotrophically (TAP). After 24h of 35°C/40°C the cells were shifted back to room temperature for 48h. 'omics samples were taken.

ARC repo for MARS testing

Fungi hijack a ubiquitous plant apoplastic endoglucanase to release a ROS scavenging β-glucan decasaccharide to subvert immune responses

Kinetic data for modeling the dynamics of the enzymes involved in animal fatty acid synthesis

In the present study we aimed at the highest possible resolution of this network by combining analysis of transcriptome, proteome and subcellularly resolved metabolome of plants that were exposed to rising carbon dioxide concentrations over a time course of one week.

A prototypic ARC that implements all specification standards accordingly

Git repository for the publication "An Ectomycorrhizal Fungus Alters Development Stages Within Pedunculate Oak’s Endogenous Growth Rhythm". For further information please read the README.md file.

early maturity 7 controls photoperiodic flowering in barley by modifying the diurnal expression pattern of the major photoperiod response gene Ppd-H1.

GridScore trial: A barley trial focusing on date-based traits. This is a good example of a simple setup.