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# Deciphering the RNA-binding protein network during endosomal mRNA transport # Deciphering the RNA-binding protein network during endosomal mRNA transport
This ARC [Annoteted Research Context](https://arc-rdm.org/) contains the original data of the Devan et al. publication.
## Original Publication ## Original Publication
S. K. Devan, S. Shanmugasundaram, K. Müntjes, S.H.J. Smits, F. Altegoer, M. Feldbrügge (2024) Deciphering the RNA-Binding protein network during endosomal mRNA transport. PNAS. 121:e240491121 S. K. Devan, S. Shanmugasundaram, K. Müntjes, S.H.J. Smits, F. Altegoer, M. Feldbrügge (2024) Deciphering the RNA-Binding protein network during endosomal mRNA transport. PNAS. 121:e240491121
https://www.pnas.org/doi/10.1073/pnas.2404091121 https://www.pnas.org/doi/10.1073/pnas.2404091121
...@@ -16,7 +18,7 @@ Microtubule-dependent endosomal transport is crucial for polar growth, ensuring ...@@ -16,7 +18,7 @@ Microtubule-dependent endosomal transport is crucial for polar growth, ensuring
## Studies ## Studies
The [Studies (S)](https://git.nfdi4plants.org/devan/2024_Devan-Sai_et_al_PNAS/-/tree/main/studies?ref_type=heads) are named after the chapters of the publication. The [Studies (S)](https://git.nfdi4plants.org/devan/2024_Devan-Sai_et_al_PNAS/-/tree/main/studies?ref_type=heads) are named after the names of the chapters in the publication.
S1_MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain S1_MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain
S2_MLLE3 of Rrm4 Recognizes PAM2-Like Sequences with a Defined Binding Pocket S2_MLLE3 of Rrm4 Recognizes PAM2-Like Sequences with a Defined Binding Pocket
...@@ -27,7 +29,7 @@ S6_Identification of Unrecognized Rrm4 Interaction Partners ...@@ -27,7 +29,7 @@ S6_Identification of Unrecognized Rrm4 Interaction Partners
S7_Human MLLE Domains Differentiate between Binding Partners S7_Human MLLE Domains Differentiate between Binding Partners
## Assays ## Assays
The [Assays](https://git.nfdi4plants.org/devan/2024_Devan-Sai_et_al_PNAS/-/tree/main/assays?ref_type=heads) folder contain the actual raw/processed data of the experiments in the *dataset* folder and the corresponding protocols in the *protocol* folder. The [Assays (A)](https://git.nfdi4plants.org/devan/2024_Devan-Sai_et_al_PNAS/-/tree/main/assays?ref_type=heads) folder contains the results of the individual experiments. The raw and processed data are stored in the `dataset` folder of the assay and the corresponding protocols are in the `protocol` folder.
### Chapter 1: MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain ### Chapter 1: MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain
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