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# Deciphering the RNA-binding protein network during endosomal mRNA transport
# Deciphering the RNA-binding protein network during endosomal mRNA transport
This ARC [Annoteted Research Context](https://arc-rdm.org/) contains the original data of the Devan et al. publication.
## Original Publication
## Original Publication
S. K. Devan, S. Shanmugasundaram, K. Müntjes, S.H.J. Smits, F. Altegoer, M. Feldbrügge (2024) Deciphering the RNA-Binding protein network during endosomal mRNA transport. PNAS. 121:e240491121
S. K. Devan, S. Shanmugasundaram, K. Müntjes, S.H.J. Smits, F. Altegoer, M. Feldbrügge (2024) Deciphering the RNA-Binding protein network during endosomal mRNA transport. PNAS. 121:e240491121
https://www.pnas.org/doi/10.1073/pnas.2404091121
https://www.pnas.org/doi/10.1073/pnas.2404091121
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## Studies
## Studies
The [Studies (S)](https://git.nfdi4plants.org/devan/2024_Devan-Sai_et_al_PNAS/-/tree/main/studies?ref_type=heads) are named after the chapters of the publication.
The [Studies (S)](https://git.nfdi4plants.org/devan/2024_Devan-Sai_et_al_PNAS/-/tree/main/studies?ref_type=heads) are named after the names of the chapters in the publication.
S1_MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain
S1_MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain
S2_MLLE3 of Rrm4 Recognizes PAM2-Like Sequences with a Defined Binding Pocket
S2_MLLE3 of Rrm4 Recognizes PAM2-Like Sequences with a Defined Binding Pocket
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S7_Human MLLE Domains Differentiate between Binding Partners
S7_Human MLLE Domains Differentiate between Binding Partners
## Assays
## Assays
The [Assays](https://git.nfdi4plants.org/devan/2024_Devan-Sai_et_al_PNAS/-/tree/main/assays?ref_type=heads) folder contain the actual raw/processed data of the experiments in the *dataset* folder and the corresponding protocols in the *protocol* folder.
The [Assays (A)](https://git.nfdi4plants.org/devan/2024_Devan-Sai_et_al_PNAS/-/tree/main/assays?ref_type=heads) folder contains the results of the individual experiments. The raw and processed data are stored in the `dataset` folder of the assay and the corresponding protocols are in the `protocol` folder.
### Chapter 1: MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain
### Chapter 1: MLLE3 of Rrm4 Constitutes a Different Type of Seven-Helix MLLE Domain