Explore ARCs

The trace element iron is essential for life, but elevated levels can rapidly cause cellular damage through oxidative stress. Bacteria, like Corynebacterium glutamicum, tightly regulate iron and heme homeostasis via the global regulators DtxR and HrrA. This study provides the first analysis of the genome-wide binding patterns of these two regulators demonstrating significant differences in binding dependent on the tested iron regimes. Overall, we identified 25 new DtxR targets and 210 previously unknown HrrA targets, including genes with crucial roles in central metabolism and DNA repair. Notably, DtxR was shown to link iron metabolism to methionine synthesis, which might be important to protect the cell from oxidative stress. Our findings highlight the interconnected nature of DtxR and HrrA networks and underscore the value of condition-specific analysis to deepen the understanding of how bacteria adapt to environmental changes. 

Characterization of the FNR-type regulator GoxR

Multi-Modal Rat MRI + Light Sheet Brain Dataset

Cofunctioning of bacterial exometabolites drives root microbiota establishment

Transcript and metabolite changes during the early phase of abscisic acid-mediated induction of crassulacean acid metabolism in Talinum triangulare

A systematic overexpression approach reveals native targets to increase squalene production in Synechocystis sp. PCC 6803

Global expression patterns of R-genes in tomato and potato

Sugar transporters spatially organize microbiota colonization along the longitudinal root axis of Arabidopsis

A GH81-type β-glucan-binding protein enhances colonization by mutualistic fungi in barley

ARC repo for MARS testing

Predmoter — cross-species prediction of plant promoter and enhancer regions

Exploring natural genetic variation in photosynthesis-related traits of barley in the field

Traits linked to natural variation of sulfur content in Arabidopsis thaliana

Reversible Burst of Transcriptional Changes during Induction of Crassulacean Acid Metabolism in Talinum triangulare.

Fungi hijack a ubiquitous plant apoplastic endoglucanase to release a ROS scavenging β-glucan decasaccharide to subvert immune responses

Kinetic data for modeling the dynamics of the enzymes involved in animal fatty acid synthesis

Host preference and invasiveness of commensal bacteria in the Lotus and Arabidopsis root microbiota

early maturity 7 controls photoperiodic flowering in barley by modifying the diurnal expression pattern of the major photoperiod response gene Ppd-H1.