update isa files

README.md

 # Chlamydomonas reinhardtii heat stress time course experiment
 
 ## Experimental design
-<img src="https://git.nfdi4plants.org/venn/Ru_ChlamyHeatstress/-/raw/main/studies/HeatstressExperiment/protocols/2022-07-12_121059.png" alt="Overview_HS40" width="80%"/>
+<img src="https://git.nfdi4plants.org/venn/Ru_ChlamyHeatstress/-/raw/main/studies/HeatstressExperiment/protocols/2022-07-12_121059.png" alt="Overview_HS40" width="70%"/>
 
-**Figure 1:** Experimental design of the heat treatment experiments (Zhang et al.)
+**Figure 1:** Experimental design of the heat treatment experiments (Zhang et al. 2022).
 
 ## Publication
 
-Title: Systems-wide analysis revealed shared and unique responses to moderate and acute high temperatures in the green alga Chlamydomonas reinhardtii. 
+#### Title
+Systems-wide analysis revealed shared and unique responses to moderate and acute high temperatures in the green alga Chlamydomonas reinhardtii. 
 
-Authors: Zhang N, Mattoon EM, McHargue W, Venn B, Zimmer D, Pecani K, Jeong J, Anderson CM, Chen C, Berry JC, Xia M, Tzeng SC, Becker E, Pazouki L, Evans B, Cross F, Cheng J, Czymmek KJ, Schroda M, Mühlhaus T, Zhang R. 
+#### Authors
+Zhang N, Mattoon EM, McHargue W, Venn B, Zimmer D, Pecani K, Jeong J, Anderson CM, Chen C, Berry JC, Xia M, Tzeng SC, Becker E, Pazouki L, Evans B, Cross F, Cheng J, Czymmek KJ, Schroda M, Mühlhaus T, Zhang R. 
+
+#### Citation
+
+Zhang N, Mattoon EM, McHargue W, Venn B, Zimmer D, Pecani K, Jeong J, Anderson CM, Chen C, Berry JC, Xia M, Tzeng SC, Becker E, Pazouki L, Evans B, Cross F, Cheng J, Czymmek KJ, Schroda M, Mühlhaus T, Zhang R. Systems-wide analysis revealed shared and unique responses to moderate and acute high temperatures in the green alga Chlamydomonas reinhardtii. Commun Biol. 2022 May 13;5(1):460. doi: 10.1038/s42003-022-03359-z . PMID: 35562408; PMCID: PMC9106746.
 
-Journal: Commun Biol. 2022 May 13;5(1):460. doi: 10.1038/s42003-022-03359-z. PMID: 35562408; PMCID: PMC9106746.
 
 ## Sampling schema