Explore ARCs

A prototypic ARC that implements all specification standards accordingly

The trace element iron is essential for life, but elevated levels can rapidly cause cellular damage through oxidative stress. Bacteria, like Corynebacterium glutamicum, tightly regulate iron and heme homeostasis via the global regulators DtxR and HrrA. This study provides the first analysis of the genome-wide binding patterns of these two regulators demonstrating significant differences in binding dependent on the tested iron regimes. Overall, we identified 25 new DtxR targets and 210 previously unknown HrrA targets, including genes with crucial roles in central metabolism and DNA repair. Notably, DtxR was shown to link iron metabolism to methionine synthesis, which might be important to protect the cell from oxidative stress. Our findings highlight the interconnected nature of DtxR and HrrA networks and underscore the value of condition-specific analysis to deepen the understanding of how bacteria adapt to environmental changes. 

Multi-Modal Rat MRI + Light Sheet Brain Dataset

A systematic overexpression approach reveals native targets to increase squalene production in Synechocystis sp. PCC 6803

Sugar transporters spatially organize microbiota colonization along the longitudinal root axis of Arabidopsis

A GH81-type β-glucan-binding protein enhances colonization by mutualistic fungi in barley

Fungi hijack a ubiquitous plant apoplastic endoglucanase to release a ROS scavenging β-glucan decasaccharide to subvert immune responses

Kinetic data for modeling the dynamics of the enzymes involved in animal fatty acid synthesis

early maturity 7 controls photoperiodic flowering in barley by modifying the diurnal expression pattern of the major photoperiod response gene Ppd-H1.

Identification of nuclear pore proteins at plasmodesmata

Physiology, biochemistry and anatomy of young fully developed leaves from Brassicaceae species with C3 and C3-C4 (C2) photosynthesis

Unraveling the sugar code: the role of microbial extracellular glycans in plant-microbe interactions

Mapping the castor bean endosperm proteome revealed a metabolic interaction between plastid, mitochondria, and peroxisomes to optimize seedling growth

"QUINOA DIVERSITY- Quinoa Phenotypic and Genotypic Diversity for Yield and Composition"

Pangenome of Camellia sinensis

RNA seq from Solanum lycopersicoides plants, performed for the manuscript entitled "A Solanum lycopersicoides reference genome facilitates insights into tomato specialized metabolism and immunity."